This HTML5 document contains 42 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n9http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00209805%3A_____%2F13%3A%230000433%21RIV14-MSM-00209805/
n20http://linked.opendata.cz/resource/domain/vavai/projekt/
n11http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n7http://linked.opendata.cz/resource/domain/vavai/subjekt/
n6http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
rdfshttp://www.w3.org/2000/01/rdf-schema#
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n16http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n8http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n19http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n14http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n18http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n17http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00209805%3A_____%2F13%3A%230000433%21RIV14-MSM-00209805
rdf:type
n6:Vysledek skos:Concept
rdfs:seeAlso
http://cebp.aacrjournals.org/content/22/9/1620.full.pdf+html
dcterms:description
Recent findings suggest that alcohol consumption may reduce risk of multiple myeloma. To better understand this relationship, we conducted an analysis of six case-control studies participating in the International Multiple Myeloma Consortium (1,567 cases, 7,296 controls). Summary ORs and 95% confidence intervals (CI) relating different measures of alcohol consumption and multiple myeloma risk were computed by unconditional logistic regression with adjustment for age, race, and study center. Cases were significantly less likely than controls to report ever drinking alcohol (men: OR 1/4 0.72; 95% CI, 0.59-0.89; women: OR 1/4 0.81; 95% CI, 0.68-0.95). The inverse association with multiple myeloma was stronger when comparing current to never drinkers (men:OR 1/4 0.57; 95% CI, 0.45-0.72; women:OR 1/4 0.55; 95% CI, 0.45-0.68), but null among former drinkers. We did not observe an exposure-response relationship with increasing alcohol frequency, duration, or cumulative lifetime consumption. Additional adjustment for body mass index, education, or smoking did not affect our results; and the patterns of association were similar for each type of alcohol beverage examined. Our study is, to our knowledge, the largest of its kind to date, and our findings suggest that alcohol consumption may be associated with reduced risk of multiple myeloma.Prospective studies, especially those conducted as pooled analyses with large sample sizes, are needed to confirm our findings and further explore whether alcohol consumption provides true biologic protection against this rare, highly fatal malignancy. Recent findings suggest that alcohol consumption may reduce risk of multiple myeloma. To better understand this relationship, we conducted an analysis of six case-control studies participating in the International Multiple Myeloma Consortium (1,567 cases, 7,296 controls). Summary ORs and 95% confidence intervals (CI) relating different measures of alcohol consumption and multiple myeloma risk were computed by unconditional logistic regression with adjustment for age, race, and study center. Cases were significantly less likely than controls to report ever drinking alcohol (men: OR 1/4 0.72; 95% CI, 0.59-0.89; women: OR 1/4 0.81; 95% CI, 0.68-0.95). The inverse association with multiple myeloma was stronger when comparing current to never drinkers (men:OR 1/4 0.57; 95% CI, 0.45-0.72; women:OR 1/4 0.55; 95% CI, 0.45-0.68), but null among former drinkers. We did not observe an exposure-response relationship with increasing alcohol frequency, duration, or cumulative lifetime consumption. Additional adjustment for body mass index, education, or smoking did not affect our results; and the patterns of association were similar for each type of alcohol beverage examined. Our study is, to our knowledge, the largest of its kind to date, and our findings suggest that alcohol consumption may be associated with reduced risk of multiple myeloma.Prospective studies, especially those conducted as pooled analyses with large sample sizes, are needed to confirm our findings and further explore whether alcohol consumption provides true biologic protection against this rare, highly fatal malignancy.
dcterms:title
A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium
skos:prefLabel
A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium
skos:notation
RIV/00209805:_____/13:#0000433!RIV14-MSM-00209805
n6:predkladatel
n7:ico%3A00209805
n3:aktivita
n14:P
n3:aktivity
P(ED2.1.00/03.0101)
n3:cisloPeriodika
9
n3:dodaniDat
n17:2014
n3:domaciTvurceVysledku
n11:1030779
n3:druhVysledku
n13:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
58948
n3:idVysledku
RIV/00209805:_____/13:#0000433
n3:jazykVysledku
n4:eng
n3:klicovaSlova
Non-Hodgkin-lymphoma; cigarette-smoking; diet; neoplasms; tobacco
n3:klicoveSlovo
n8:neoplasms n8:cigarette-smoking n8:Non-Hodgkin-lymphoma n8:tobacco n8:diet
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[AE70200DF006]
n3:nazevZdroje
Cancer Epidemiology, Biomarkers and Prevention
n3:obor
n18:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
29
n3:projekt
n20:ED2.1.00%2F03.0101
n3:rokUplatneniVysledku
n17:2013
n3:svazekPeriodika
22
n3:tvurceVysledku
Foretová, Lenka
n3:wos
000324674500015
s:issn
1055-9965
s:numberOfPages
8
n16:doi
10.1158/1055-9965.EPI-13-0334