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Statements

Subject Item
n2:RIV%2F00209805%3A_____%2F12%3A%230000324%21RIV13-MSM-00209805
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://annonc.oxfordjournals.org/content/23/9/2362.long
dcterms:description
The two most common forms of non-Hodgkin lymphoma (NHL) exhibit different sex ratios: diffuse large B-cell lymphoma (DLBCL) occurs more frequently in men and follicular lymphoma (FL) more frequently in women. Looking among women alone, this pooled analysis explores the relationship between reproductive histories and these cancers. Self-reported reproductive histories from 4263 women with NHL and 5971 women without NHL were pooled across 18 case–control studies (1983–2005) from North America, Europe and Japan. Study-specific odd ratios (ORs) and confidence intervals (CIs) were estimated using logistic regression and pooled using randomeffects meta-analyses. Associations with reproductive factors were found for FL rather than NHL overall and DLBCL. In particular, the risk of FL decreased with increasing number of pregnancies (pooled ORtrend = 0.88, 95% CI 0.81–0.96). FL was associated with hormonal contraception (pooled OR = 1.30, 95% CI 1.04–1.63), and risks were increased when use started after the age of 21, was used for <5 years or stopped for >20 years before diagnosis. DLBCL, on the other hand, was not associated with hormonal contraception (pooled OR = 0.87, 95% CI 0.65–1.16). Hormonal contraception is associated with an increased risk of FL but not of DLBCL or NHL overall. The two most common forms of non-Hodgkin lymphoma (NHL) exhibit different sex ratios: diffuse large B-cell lymphoma (DLBCL) occurs more frequently in men and follicular lymphoma (FL) more frequently in women. Looking among women alone, this pooled analysis explores the relationship between reproductive histories and these cancers. Self-reported reproductive histories from 4263 women with NHL and 5971 women without NHL were pooled across 18 case–control studies (1983–2005) from North America, Europe and Japan. Study-specific odd ratios (ORs) and confidence intervals (CIs) were estimated using logistic regression and pooled using randomeffects meta-analyses. Associations with reproductive factors were found for FL rather than NHL overall and DLBCL. In particular, the risk of FL decreased with increasing number of pregnancies (pooled ORtrend = 0.88, 95% CI 0.81–0.96). FL was associated with hormonal contraception (pooled OR = 1.30, 95% CI 1.04–1.63), and risks were increased when use started after the age of 21, was used for <5 years or stopped for >20 years before diagnosis. DLBCL, on the other hand, was not associated with hormonal contraception (pooled OR = 0.87, 95% CI 0.65–1.16). Hormonal contraception is associated with an increased risk of FL but not of DLBCL or NHL overall.
dcterms:title
Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies
skos:prefLabel
Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies
skos:notation
RIV/00209805:_____/12:#0000324!RIV13-MSM-00209805
n17:predkladatel
n18:ico%3A00209805
n3:aktivita
n19:P
n3:aktivity
P(ED2.1.00/03.0101)
n3:cisloPeriodika
9
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n4:1030779
n3:druhVysledku
n20:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
149340
n3:idVysledku
RIV/00209805:_____/12:#0000324
n3:jazykVysledku
n15:eng
n3:klicovaSlova
case-control studies; diffuse large B-cell lymphoma; follicular lymphoma; hormonal contraceptives; non-Hodgkin lymphoma; reproductive history
n3:klicoveSlovo
n9:follicular%20lymphoma n9:non-Hodgkin%20lymphoma n9:reproductive%20history n9:diffuse%20large%20B-cell%20lymphoma n9:case-control%20studies n9:hormonal%20contraceptives
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[381B90B7DBAE]
n3:nazevZdroje
Annals of oncology
n3:obor
n10:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
23
n3:projekt
n14:ED2.1.00%2F03.0101
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
23
n3:tvurceVysledku
Foretová, Lenka Kane, E. V.
n3:wos
000308017000024
s:issn
0923-7534
s:numberOfPages
13
n5:doi
10.1093/annonc/mds171