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Statements

Subject Item
n2:RIV%2F00209805%3A_____%2F12%3A%230000307%21RIV13-MSM-00209805
rdf:type
skos:Concept n10:Vysledek
rdfs:seeAlso
http://www.linkos.cz/files/klinicka-onkologie/174/4137.pdf
dcterms:description
We introduce the national research biobanking infrastructure, BBMRI_CZ. The infrastructure has been founded by the Ministry of Education and became a partner of the European biobanking infrastructure BBMRI.eu. It is designed as a network of individual biobanks where each biobank stores samples obtained from associated healthcare providers. The biobanks comprise long term storage (various types of tissues classified by diagnosis, serum at surgery, genomic DNA and RNA) and short term storage (longitudinally sampled patient sera). We discuss the operation workflow of the infrastructure that needs to be the distributed system: transfer of the samples to the biobank needs to be accompanied by extraction of data from the hospital information systems and this data must be stored in a central index serving mainly for sample lookup. Since BBMRI_CZ is designed solely for research purposes, the data is anonymised prior to their integration into the central BBMRI_CZ index. The index is then available for registered researchers to seek for samples of interest and to request the samples from biobank managers. The paper provides an overview of the structure of data stored in the index. We also discuss monitoring system for the biobanks, incorporated to ensure quality of the stored samples. We introduce the national research biobanking infrastructure, BBMRI_CZ. The infrastructure has been founded by the Ministry of Education and became a partner of the European biobanking infrastructure BBMRI.eu. It is designed as a network of individual biobanks where each biobank stores samples obtained from associated healthcare providers. The biobanks comprise long term storage (various types of tissues classified by diagnosis, serum at surgery, genomic DNA and RNA) and short term storage (longitudinally sampled patient sera). We discuss the operation workflow of the infrastructure that needs to be the distributed system: transfer of the samples to the biobank needs to be accompanied by extraction of data from the hospital information systems and this data must be stored in a central index serving mainly for sample lookup. Since BBMRI_CZ is designed solely for research purposes, the data is anonymised prior to their integration into the central BBMRI_CZ index. The index is then available for registered researchers to seek for samples of interest and to request the samples from biobank managers. The paper provides an overview of the structure of data stored in the index. We also discuss monitoring system for the biobanks, incorporated to ensure quality of the stored samples.
dcterms:title
The Biobanking Research Infrastructure BBMRI_CZ: a critical tool to enhance translational cancer research The Biobanking Research Infrastructure BBMRI_CZ: a critical tool to enhance translational cancer research
skos:prefLabel
The Biobanking Research Infrastructure BBMRI_CZ: a critical tool to enhance translational cancer research The Biobanking Research Infrastructure BBMRI_CZ: a critical tool to enhance translational cancer research
skos:notation
RIV/00209805:_____/12:#0000307!RIV13-MSM-00209805
n10:predkladatel
n11:ico%3A00209805
n3:aktivita
n16:P
n3:aktivity
P(ED2.1.00/03.0101), P(LM2010004)
n3:cisloPeriodika
supplementum 2
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n13:2486725 n13:5270340 n13:4058062 n13:5713021
n3:druhVysledku
n15:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
124986
n3:idVysledku
RIV/00209805:_____/12:#0000307
n3:jazykVysledku
n14:eng
n3:klicovaSlova
biobanking; databases; cancer research
n3:klicoveSlovo
n12:biobanking n12:cancer%20research n12:databases
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[717E8C9CE54D]
n3:nazevZdroje
Klinická onkologie
n3:obor
n19:FD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:projekt
n8:ED2.1.00%2F03.0101 n8:LM2010004
n3:rokUplatneniVysledku
n7:2012
n3:svazekPeriodika
25
n3:tvurceVysledku
Nenutil, Rudolf Knoflíčková, Dana Greplová, Kristína Valík, Dalibor
s:issn
0862-495X
s:numberOfPages
4