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Statements

Subject Item
n2:RIV%2F00179906%3A_____%2F12%3A10124604%21RIV13-MZ0-00179906
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1016/j.ajog.2012.01.004
dcterms:description
The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification technique used. CONCLUSION: The intensity of intraamniotic inflammatory response to genital mycoplasmas decreased with gestational age. The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification technique used. CONCLUSION: The intensity of intraamniotic inflammatory response to genital mycoplasmas decreased with gestational age.
dcterms:title
The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation
skos:prefLabel
The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation
skos:notation
RIV/00179906:_____/12:10124604!RIV13-MZ0-00179906
n17:predkladatel
n18:ico%3A00179906
n4:aktivita
n20:I n20:P
n4:aktivity
I, P(GA304/09/0494), P(NS10382)
n4:cisloPeriodika
4
n4:dodaniDat
n9:2013
n4:domaciTvurceVysledku
n13:4471113 n13:6453562 n13:1807676
n4:druhVysledku
n16:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n11:predkladatel
n4:idSjednocenehoVysledku
140714
n4:idVysledku
RIV/00179906:_____/12:10124604
n4:jazykVysledku
n12:eng
n4:klicovaSlova
threshold cycle; molecular microbiology; amniotic fluid; onset; rupture; hominis; culture; membranes; preterm labor; clinical-significance; ureaplasma-urealyticum; polymerase-chain-reaction
n4:klicoveSlovo
n5:culture n5:preterm%20labor n5:amniotic%20fluid n5:threshold%20cycle n5:membranes n5:polymerase-chain-reaction n5:clinical-significance n5:ureaplasma-urealyticum n5:hominis n5:rupture n5:onset n5:molecular%20microbiology
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[B6F6E51E7355]
n4:nazevZdroje
American Journal of Obstetrics and Gynecology
n4:obor
n19:FK
n4:pocetDomacichTvurcuVysledku
3
n4:pocetTvurcuVysledku
7
n4:projekt
n8:NS10382 n8:GA304%2F09%2F0494
n4:rokUplatneniVysledku
n9:2012
n4:svazekPeriodika
206
n4:tvurceVysledku
Hougaard, David M. Kacerovský, Marian Plíšková, Lenka Jacobsson, Bo Skogstrand, Kristin Bolehovská, Radka Tsiartas, Panagiotis
n4:wos
000302266000029
s:issn
0002-9378
s:numberOfPages
8
n10:doi
10.1016/j.ajog.2012.01.004