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Statements

Subject Item
n2:RIV%2F00179906%3A_____%2F12%3A10123575%21RIV13-MZ0-00179906
rdf:type
n18:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.1155/2012/152895
dcterms:description
Interleukin-10 (IL-10) is considered to be a cytokine with potent anti-inflammatory properties, which have been previously linked to increased incidence of sepsis. The level of IL-10 is elevated by cardiac surgery when cardiopulmonary bypass (CPB) and methylprednisolone are used. In our study, we compare the level of IL-10, IL-10 Receptor (IL-10R), and percentage of neutrophils between two groups of cardiac surgical patients undergoing Coronary Artery Bypass Grafting, both of which were not given methylprednisolone. The first group was operated with conventional CPB, while the second group was operated with minimally invasive CPB (mini-CPB). We detected enhanced level of IL-10 during surgery and at the end of surgery in both groups of patients. While no correlation between IL-10 and IL10R was found, IL-10 was positively correlated with increased percentage of neutrophils at the time points when the level of IL-10 peaked. Interleukin-10 (IL-10) is considered to be a cytokine with potent anti-inflammatory properties, which have been previously linked to increased incidence of sepsis. The level of IL-10 is elevated by cardiac surgery when cardiopulmonary bypass (CPB) and methylprednisolone are used. In our study, we compare the level of IL-10, IL-10 Receptor (IL-10R), and percentage of neutrophils between two groups of cardiac surgical patients undergoing Coronary Artery Bypass Grafting, both of which were not given methylprednisolone. The first group was operated with conventional CPB, while the second group was operated with minimally invasive CPB (mini-CPB). We detected enhanced level of IL-10 during surgery and at the end of surgery in both groups of patients. While no correlation between IL-10 and IL10R was found, IL-10 was positively correlated with increased percentage of neutrophils at the time points when the level of IL-10 peaked.
dcterms:title
The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting
skos:prefLabel
The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting
skos:notation
RIV/00179906:_____/12:10123575!RIV13-MZ0-00179906
n18:predkladatel
n21:ico%3A00179906
n3:aktivita
n16:Z n16:P n16:I
n3:aktivity
I, P(NR9090), Z(MSM0021620812)
n3:cisloPeriodika
2012
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n4:1730452 n4:7813813 n4:3854280 n4:6032389
n3:druhVysledku
n19:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
132980
n3:idVysledku
RIV/00179906:_____/12:10123575
n3:jazykVysledku
n13:eng
n3:klicovaSlova
sepsis; release; survival; receptors; macrophages; alpha; association; interleukin-10; IL-10; cardiac-surgery
n3:klicoveSlovo
n7:survival n7:cardiac-surgery n7:IL-10 n7:macrophages n7:sepsis n7:release n7:interleukin-10 n7:alpha n7:receptors n7:association
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[5DDBA1646E08]
n3:nazevZdroje
Mediators of Inflammation
n3:obor
n10:FN
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
7
n3:projekt
n20:NR9090
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
Neuveden
n3:tvurceVysledku
Lonský, Vladimír Krejsek, Jan Koláčková, Martina Manďák, Jiří Kuneš, Pavel Svitek, Vladimír Holubcová, Zdeňka
n3:wos
000301419000001
n3:zamer
n17:MSM0021620812
s:issn
0962-9351
s:numberOfPages
8
n5:doi
10.1155/2012/152895