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Statements

Subject Item
n2:RIV%2F00179906%3A_____%2F10%3A10069732%21RIV11-MZ0-00179906
rdf:type
skos:Concept n13:Vysledek
dcterms:description
In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318 In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318
dcterms:title
Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass
skos:prefLabel
Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass
skos:notation
RIV/00179906:_____/10:10069732!RIV11-MZ0-00179906
n4:aktivita
n7:P n7:Z
n4:aktivity
P(NR9090), Z(MSM0021620812)
n4:cisloPeriodika
1
n4:dodaniDat
n8:2011
n4:domaciTvurceVysledku
n5:8222525 n5:2536846 n5:7584881 n5:3854280 n5:1730452
n4:druhVysledku
n9:J
n4:duvernostUdaju
n11:S
n4:entitaPredkladatele
n14:predkladatel
n4:idSjednocenehoVysledku
294493
n4:idVysledku
RIV/00179906:_____/10:10069732
n4:jazykVysledku
n17:eng
n4:klicovaSlova
apoptosis; Apo/Fas complex; neutrophil; inflammation; cardiac surgery
n4:klicoveSlovo
n12:Apo%2FFas%20complex n12:cardiac%20surgery n12:apoptosis n12:inflammation n12:neutrophil
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[DA17DA3D4023]
n4:nazevZdroje
Perfusion
n4:obor
n16:FA
n4:pocetDomacichTvurcuVysledku
5
n4:pocetTvurcuVysledku
7
n4:projekt
n10:NR9090
n4:rokUplatneniVysledku
n8:2010
n4:svazekPeriodika
25
n4:tvurceVysledku
Manďák, Jiří Andrýs, Ctirad Harrer, Jan Kuneš, Pavel Krejsek, Jan Koláčková, Martina Holická, Monika
n4:wos
000275458800008
n4:zamer
n15:MSM0021620812
s:issn
0267-6591
s:numberOfPages
6