This HTML5 document contains 42 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n10http://linked.opendata.cz/ontology/domain/vavai/
n15http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n12http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n8http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00179906%3A_____%2F10%3A10051465%21RIV11-MZ0-00179906/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n11http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00179906%3A_____%2F10%3A10051465%21RIV11-MZ0-00179906
rdf:type
skos:Concept n10:Vysledek
dcterms:description
Congenital disorders of glycosylation (CDG) are a group of clinically and biochemically diverse defects. The current screening methods (based on analysis of transferrin),which are used postnatally for the most frequent types, are however not suitable for prenatal diagnosis. The aim of the study was to investigate whether alterations in the microheterogeneity of alpha-fetoprotein in amniotic fluid would provide more reliable results. Isoelectric focusing with direct immunofixation and silver staining was used for analyses. A difference in the relative proportion of individual alpha-fetoprotein bands (particularly increase of band II density) was found in a case where CDG has been diagnosed postnatally, and in two other samples from pregnancies which resulted in termination, without further examination. Verification of our results in another laboratory with the exclusion of several potentially pertinent variables is advisable. Congenital disorders of glycosylation (CDG) are a group of clinically and biochemically diverse defects. The current screening methods (based on analysis of transferrin),which are used postnatally for the most frequent types, are however not suitable for prenatal diagnosis. The aim of the study was to investigate whether alterations in the microheterogeneity of alpha-fetoprotein in amniotic fluid would provide more reliable results. Isoelectric focusing with direct immunofixation and silver staining was used for analyses. A difference in the relative proportion of individual alpha-fetoprotein bands (particularly increase of band II density) was found in a case where CDG has been diagnosed postnatally, and in two other samples from pregnancies which resulted in termination, without further examination. Verification of our results in another laboratory with the exclusion of several potentially pertinent variables is advisable.
dcterms:title
Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia
skos:prefLabel
Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia
skos:notation
RIV/00179906:_____/10:10051465!RIV11-MZ0-00179906
n3:aktivita
n16:V n16:Z
n3:aktivity
V, Z(MZ0FNHK2005)
n3:cisloPeriodika
9
n3:dodaniDat
n11:2011
n3:domaciTvurceVysledku
n6:4215613 n6:1290177
n3:druhVysledku
n9:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
246115
n3:idVysledku
RIV/00179906:_____/10:10051465
n3:jazykVysledku
n12:eng
n3:klicovaSlova
prenatal diagnosis; isoelectric focusing; congenital disorders of glycosylation; amniotic fluid; alpha-fetoprotein
n3:klicoveSlovo
n7:alpha-fetoprotein n7:isoelectric%20focusing n7:congenital%20disorders%20of%20glycosylation n7:amniotic%20fluid n7:prenatal%20diagnosis
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[EF4049BF82A8]
n3:nazevZdroje
Clinical Chemistry and Laboratory Medicine
n3:obor
n13:FG
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n11:2010
n3:svazekPeriodika
48
n3:tvurceVysledku
Albahri, Ziad Marklová, Eliška
n3:wos
000283183300015
n3:zamer
n15:MZ0FNHK2005
s:issn
1434-6621
s:numberOfPages
5