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Statements

Subject Item
n2:RIV%2F00179906%3A_____%2F10%3A10033220%21RIV11-MZ0-00179906
rdf:type
n11:Vysledek skos:Concept
dcterms:description
Heritability of human personality traits is estimated in the range from 30% to 60%. A polygenic model which suggests interactions of multiple genes with each other and environment is recently preferred by researches. One of the reasons why a psychiatrist should be aware of this issue is that personality traits of healthy persons may represent endophenotypes of psychopatology, and thus predict potential mental health problems. This review covers genetic background of major human personality traits like novelty seeking, neuroticism, extraversion, impulsivity, or antisocial behavior. Results of recent meta-analyses with potential neurobiological mechanisms and possible transitions to Axis I mental disorders are presented. A full understanding of genetic principles of the human personality and the role of social environment may be a fundamental step to an effective causal treatment and prevention of mental disorders in the future. Heritability of human personality traits is estimated in the range from 30% to 60%. A polygenic model which suggests interactions of multiple genes with each other and environment is recently preferred by researches. One of the reasons why a psychiatrist should be aware of this issue is that personality traits of healthy persons may represent endophenotypes of psychopatology, and thus predict potential mental health problems. This review covers genetic background of major human personality traits like novelty seeking, neuroticism, extraversion, impulsivity, or antisocial behavior. Results of recent meta-analyses with potential neurobiological mechanisms and possible transitions to Axis I mental disorders are presented. A full understanding of genetic principles of the human personality and the role of social environment may be a fundamental step to an effective causal treatment and prevention of mental disorders in the future.
dcterms:title
Genetics of the Human Personality Genetics of the Human Personality
skos:prefLabel
Genetics of the Human Personality Genetics of the Human Personality
skos:notation
RIV/00179906:_____/10:10033220!RIV11-MZ0-00179906
n3:aktivita
n9:V n9:Z
n3:aktivity
V, Z(MZ0FNHK2005)
n3:cisloPeriodika
1
n3:dodaniDat
n4:2011
n3:domaciTvurceVysledku
n10:8573409
n3:druhVysledku
n15:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
260449
n3:idVysledku
RIV/00179906:_____/10:10033220
n3:jazykVysledku
n16:eng
n3:klicovaSlova
human personality; Genetics
n3:klicoveSlovo
n7:human%20personality n7:Genetics
n3:kodStatuVydavatele
SK - Slovenská republika
n3:kontrolniKodProRIV
[089D99F729FE]
n3:nazevZdroje
Activitas Nervosa Superior Rediviva
n3:obor
n13:FL
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n4:2010
n3:svazekPeriodika
52
n3:tvurceVysledku
Hosáková, Jiřina Hosák, Ladislav
n3:zamer
n17:MZ0FNHK2005
s:issn
1337-933X
s:numberOfPages
7