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Statements

Subject Item
n2:RIV%2F00177016%3A_____%2F12%3A%230000572%21RIV13-MSM-00177016
rdf:type
n3:Vysledek skos:Concept
rdfs:seeAlso
http://iopscience.iop.org/0026-1394/49/5/S231
dcterms:description
Two radiochromic gel dosimeters, Fricke-xylenol orange (FXO) gel and Turnbull Blue (TB) gel, were studied in the scope of the iMERA+ project “Increasing cancer treatment efficacy using 3D brachytherapy” for their feasibility for determination of 3D dose distributions in brachytherapy. Initially, the dose, dose-rate and energy dependence of the gels was investigated. Subsequently, the gels were irradiated by point low-dose-rate source IsoSeed I25.S16 (125I) and high-dose-rate source GammaMed+ (192Ir) and scanned using an optical computed tomography. Optical transmission images of irradiated gels were processed to obtain optical density maps inside the gels which are proportional to the absorbed dose. With pixel resolution of 0.25 mm the detailed 3D dose distributions were reconstructed. The radial dose function between 1.5 and 35 mm from the source and anisotropy function at 10 mm radius were determined and compared to Monte Carlo calculations and TG-43 reference data showing a good agreement. Results revealed that the TB gel conserves sharp dose gradients occurring in the close proximity to the source as this gel does not suffer diffusion of dye created upon irradiation. On the other hand, FXO gel underestimates doses closer than 5 mm from the source due to diffusion, but it has a significantly higher sensitivity which enables convenient measurement of relative doses up to 35 mm from the source. Promising results can already be achieved, as demonstrated in this paper, but further development, especially on gel compositions, has to be carried out. Two radiochromic gel dosimeters, Fricke-xylenol orange (FXO) gel and Turnbull Blue (TB) gel, were studied in the scope of the iMERA+ project “Increasing cancer treatment efficacy using 3D brachytherapy” for their feasibility for determination of 3D dose distributions in brachytherapy. Initially, the dose, dose-rate and energy dependence of the gels was investigated. Subsequently, the gels were irradiated by point low-dose-rate source IsoSeed I25.S16 (125I) and high-dose-rate source GammaMed+ (192Ir) and scanned using an optical computed tomography. Optical transmission images of irradiated gels were processed to obtain optical density maps inside the gels which are proportional to the absorbed dose. With pixel resolution of 0.25 mm the detailed 3D dose distributions were reconstructed. The radial dose function between 1.5 and 35 mm from the source and anisotropy function at 10 mm radius were determined and compared to Monte Carlo calculations and TG-43 reference data showing a good agreement. Results revealed that the TB gel conserves sharp dose gradients occurring in the close proximity to the source as this gel does not suffer diffusion of dye created upon irradiation. On the other hand, FXO gel underestimates doses closer than 5 mm from the source due to diffusion, but it has a significantly higher sensitivity which enables convenient measurement of relative doses up to 35 mm from the source. Promising results can already be achieved, as demonstrated in this paper, but further development, especially on gel compositions, has to be carried out.
dcterms:title
Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources
skos:prefLabel
Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources Feasibility of radiochromic gels for 3D dosimetry of brachytherapy sources
skos:notation
RIV/00177016:_____/12:#0000572!RIV13-MSM-00177016
n3:predkladatel
n15:ico%3A00177016
n5:aktivita
n19:R
n5:aktivity
R
n5:cisloPeriodika
5
n5:dodaniDat
n14:2013
n5:domaciTvurceVysledku
n8:1370391 n8:5108748
n5:druhVysledku
n18:J
n5:duvernostUdaju
n17:S
n5:entitaPredkladatele
n10:predkladatel
n5:idSjednocenehoVysledku
136292
n5:idVysledku
RIV/00177016:_____/12:#0000572
n5:jazykVysledku
n7:eng
n5:klicovaSlova
Gel dosimetry; brachytherapy; radiochromic gels; iMERA+
n5:klicoveSlovo
n6:brachytherapy n6:radiochromic%20gels n6:Gel%20dosimetry n6:iMERA%2B
n5:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n5:kontrolniKodProRIV
[3F51AC161C7A]
n5:nazevZdroje
Metrologia
n5:obor
n11:BG
n5:pocetDomacichTvurcuVysledku
2
n5:pocetTvurcuVysledku
2
n5:rokUplatneniVysledku
n14:2012
n5:svazekPeriodika
49
n5:tvurceVysledku
Sochor, Vladimír Šolc, Jaroslav
s:issn
0026-1394
s:numberOfPages
6
n4:doi
10.1088/0026-1394/49/5/S231