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Statements

Subject Item
n2:RIV%2F00159816%3A_____%2F14%3A00060948%21RIV15-MSM-00159816
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Background and Objective. Despite the fact that the molecular mechanism of low-level laser therapy (LLLT) is not yet known, the exploitation of phototherapy in clinical medicine and surgery is of great interest. The present study investigates the effects of LLLT on open skin wound healing in normal and diabetic rats. Materials and Methods. Four round full-thickness skin wounds on dorsum were performed in male adult nondiabetic (n = 24) and diabetic (n = 24) Sprague-Dawley rats. AlGaInP (635 nm, wavelength; 5 J/cm(2), daily dose) was used to deliver power densities of 1, 5, and 15 mW/cm(2) three times daily until euthanasia. Results. PMNL infiltration was lower in the irradiated groups (15 mW/cm(2)). The synthesis and organisation of collagen fibres were consecutively enhanced in the 5 mW/cm(2) and 15 mW/cm(2) groups compared to the others in nondiabetic rats. In the diabetic group the only significant difference was recorded in the ratio PMNL/Ma at 15 mW/cm(2). A significant difference in the number of newly formed capillaries in the irradiated group (5, 15 mW/cm(2)) was recorded on day six after injury compared to the control group. Conclusion. LLLT confers a protective effect against excessive inflammatory tissue response; it stimulates neovascularization and the early formation of collagen fibres. Background and Objective. Despite the fact that the molecular mechanism of low-level laser therapy (LLLT) is not yet known, the exploitation of phototherapy in clinical medicine and surgery is of great interest. The present study investigates the effects of LLLT on open skin wound healing in normal and diabetic rats. Materials and Methods. Four round full-thickness skin wounds on dorsum were performed in male adult nondiabetic (n = 24) and diabetic (n = 24) Sprague-Dawley rats. AlGaInP (635 nm, wavelength; 5 J/cm(2), daily dose) was used to deliver power densities of 1, 5, and 15 mW/cm(2) three times daily until euthanasia. Results. PMNL infiltration was lower in the irradiated groups (15 mW/cm(2)). The synthesis and organisation of collagen fibres were consecutively enhanced in the 5 mW/cm(2) and 15 mW/cm(2) groups compared to the others in nondiabetic rats. In the diabetic group the only significant difference was recorded in the ratio PMNL/Ma at 15 mW/cm(2). A significant difference in the number of newly formed capillaries in the irradiated group (5, 15 mW/cm(2)) was recorded on day six after injury compared to the control group. Conclusion. LLLT confers a protective effect against excessive inflammatory tissue response; it stimulates neovascularization and the early formation of collagen fibres.
dcterms:title
Effect of Equal Daily Doses Achieved by Different Power Densities of Low-Level Laser Therapy at 635 nm on Open Skin Wound Healing in Normal and Diabetic Rats Effect of Equal Daily Doses Achieved by Different Power Densities of Low-Level Laser Therapy at 635 nm on Open Skin Wound Healing in Normal and Diabetic Rats
skos:prefLabel
Effect of Equal Daily Doses Achieved by Different Power Densities of Low-Level Laser Therapy at 635 nm on Open Skin Wound Healing in Normal and Diabetic Rats Effect of Equal Daily Doses Achieved by Different Power Densities of Low-Level Laser Therapy at 635 nm on Open Skin Wound Healing in Normal and Diabetic Rats
skos:notation
RIV/00159816:_____/14:00060948!RIV15-MSM-00159816
n3:aktivita
n8:P
n3:aktivity
P(ED1.100/02/0123)
n3:cisloPeriodika
January
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n12:9514325
n3:druhVysledku
n9:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
13255
n3:idVysledku
RIV/00159816:_____/14:00060948
n3:jazykVysledku
n15:eng
n3:klicovaSlova
mellitus; mechanisms; proliferation; photostimulation; photobiomodulation; radiation; intensity; irradiation; tensile-strength; helium-neon laser
n3:klicoveSlovo
n4:photobiomodulation n4:mechanisms n4:photostimulation n4:tensile-strength n4:proliferation n4:irradiation n4:intensity n4:mellitus n4:helium-neon%20laser n4:radiation
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[8568CA1D9FB9]
n3:nazevZdroje
BioMed Research International
n3:obor
n18:EE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
9
n3:projekt
n14:ED1.100%2F02%2F0123
n3:rokUplatneniVysledku
n7:2014
n3:svazekPeriodika
2014
n3:tvurceVysledku
Radonak, Jozef Kružliak, Peter Lakyova, Lucia Longauer, František Vidova, Martina Sabo, Jan Lacjakova, Kamila Kilik, Robert Vasilenko, Tomas
n3:wos
000330404400001
s:issn
2314-6133
s:numberOfPages
9
n13:doi
10.1155/2014/269253