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Statements

Subject Item
n2:RIV%2F00159816%3A_____%2F12%3A00060924%21RIV14-MZ0-00159816
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Background: An important consequence of sleep-disordered breathing (SDB) is excessive daytime sleepiness (EDS). EDS often predicts a favorable response to treatment of SDB, although in the setting of cardiovascular disease, particularly heart failure, SDB and EDS do not reliably correlate. Atrial fibrillation (AF). is another highly prevalent condition strongly associated with SDB. We sought to assess the relationship between EDS and SDB in patients with AF. Methods: We conducted a prospective study of 151 patients referred for direct current cardioversion for AF who also underwent sleep evaluation and nocturnal polysomnography. The Epworth Sleepiness Scale (ESS) was administered prior to polysomnography and considered positive if the score was >= 11. The apnea-hypopnea index (AHI) was tested for correlation with the ESS, with a cutoff of >= 5 events/h for the diagnosis of SDB. Results: Among the study participants, mean age was 69.1 +/- 11.7 years, mean BMI was 34.1 +/- 8.4 kg/m(2), and 76% were men. The prevalence of SDB in this population was 81.4%, and 35% had EDS. The association between ESS score and AHI was low (R-2 = 0.014, P = .64). The sensitivity and specificity of the ESS for the detection of SDB in patients with AF were 32.2% and 54.5%, respectively. Conclusions: Despite a high prevalence of SDB in this population with AF, most patients do not report EDS. Furthermore, EDS does not appear to correlate with severity of SDB or to accurately predict the presence of SDB. Further research is needed to determine whether EDS affects the natural history of AF or modifies the response to SDB treatment. CHEST 2012; 141(4):967-973 Background: An important consequence of sleep-disordered breathing (SDB) is excessive daytime sleepiness (EDS). EDS often predicts a favorable response to treatment of SDB, although in the setting of cardiovascular disease, particularly heart failure, SDB and EDS do not reliably correlate. Atrial fibrillation (AF). is another highly prevalent condition strongly associated with SDB. We sought to assess the relationship between EDS and SDB in patients with AF. Methods: We conducted a prospective study of 151 patients referred for direct current cardioversion for AF who also underwent sleep evaluation and nocturnal polysomnography. The Epworth Sleepiness Scale (ESS) was administered prior to polysomnography and considered positive if the score was >= 11. The apnea-hypopnea index (AHI) was tested for correlation with the ESS, with a cutoff of >= 5 events/h for the diagnosis of SDB. Results: Among the study participants, mean age was 69.1 +/- 11.7 years, mean BMI was 34.1 +/- 8.4 kg/m(2), and 76% were men. The prevalence of SDB in this population was 81.4%, and 35% had EDS. The association between ESS score and AHI was low (R-2 = 0.014, P = .64). The sensitivity and specificity of the ESS for the detection of SDB in patients with AF were 32.2% and 54.5%, respectively. Conclusions: Despite a high prevalence of SDB in this population with AF, most patients do not report EDS. Furthermore, EDS does not appear to correlate with severity of SDB or to accurately predict the presence of SDB. Further research is needed to determine whether EDS affects the natural history of AF or modifies the response to SDB treatment. CHEST 2012; 141(4):967-973
dcterms:title
Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Patients With Atrial Fibrillation Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Patients With Atrial Fibrillation
skos:prefLabel
Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Patients With Atrial Fibrillation Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Patients With Atrial Fibrillation
skos:notation
RIV/00159816:_____/12:00060924!RIV14-MZ0-00159816
n16:predkladatel
n19:ico%3A00159816
n3:aktivita
n8:P
n3:aktivity
P(ED1.100/02/0123), P(NS10098)
n3:cisloPeriodika
4
n3:dodaniDat
n9:2014
n3:domaciTvurceVysledku
n14:7343531
n3:druhVysledku
n4:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
168444
n3:idVysledku
RIV/00159816:_____/12:00060924
n3:jazykVysledku
n17:eng
n3:klicovaSlova
prevalence; population; hypertension; obesity; association; apnea; controlled-trial; risk-factors; heart-failure; positive airway pressure
n3:klicoveSlovo
n5:obesity n5:hypertension n5:risk-factors n5:controlled-trial n5:apnea n5:heart-failure n5:population n5:association n5:positive%20airway%20pressure n5:prevalence
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[570590C6E756]
n3:nazevZdroje
Chest
n3:obor
n13:FA
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
11
n3:projekt
n11:NS10098 n11:ED1.100%2F02%2F0123
n3:rokUplatneniVysledku
n9:2012
n3:svazekPeriodika
141
n3:tvurceVysledku
Friedman, Paul Konečný, Tomas Pressman, Gregg S. Kára, Tomáš Somers, Virend K. Caples, Sean M. Lopez-Jimenez, Francisco Calvin, Andrew D. Ammash, Naser Kuniyoshi, Fatima H. Sert Albuquerque, Felipe N.
n3:wos
000302592700022
s:issn
0012-3692
s:numberOfPages
7
n10:doi
10.1378/chest.11-0975