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Statements

Subject Item
n2:RIV%2F00159816%3A_____%2F10%3A%230000560%21RIV11-MZ0-00159816
rdf:type
skos:Concept n12:Vysledek
dcterms:description
Ischemic stroke is most often caused by an acute extracranial or intracranial thromboembolic lesion obstructing an artery. It has been demonstrated that recanalization is the most important modifiable predictor of a good clinical outcome. Reperfusion strategies focus on early reopening of the vessel to reestablish antegrade flow within the penumbra. Current standard therapy within 4.5 h is intravenous thrombolysis (IVT) with tissue plasminogen activator (tPA, 0.9 mg/kg body weight, maximum dose 90 mg). Thrombolytic therapy appears to be safe and effective across various types of hospitals, if the treatment is conducted by a physician with stroke expertise. Ischemic stroke is most often caused by an acute extracranial or intracranial thromboembolic lesion obstructing an artery. It has been demonstrated that recanalization is the most important modifiable predictor of a good clinical outcome. Reperfusion strategies focus on early reopening of the vessel to reestablish antegrade flow within the penumbra. Current standard therapy within 4.5 h is intravenous thrombolysis (IVT) with tissue plasminogen activator (tPA, 0.9 mg/kg body weight, maximum dose 90 mg). Thrombolytic therapy appears to be safe and effective across various types of hospitals, if the treatment is conducted by a physician with stroke expertise.
dcterms:title
Reperfusion Therapies for Acute Ischemic Stroke Reperfusion Therapies for Acute Ischemic Stroke
skos:prefLabel
Reperfusion Therapies for Acute Ischemic Stroke Reperfusion Therapies for Acute Ischemic Stroke
skos:notation
RIV/00159816:_____/10:#0000560!RIV11-MZ0-00159816
n4:aktivita
n10:V
n4:aktivity
V
n4:cisloPeriodika
2
n4:dodaniDat
n8:2011
n4:domaciTvurceVysledku
n11:1982621 n11:5260965
n4:druhVysledku
n14:J
n4:duvernostUdaju
n9:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
284838
n4:idVysledku
RIV/00159816:_____/10:#0000560
n4:jazykVysledku
n15:eng
n4:klicovaSlova
TISSUE-PLASMINOGEN-ACTIVATOR, MECHANICAL THROMBECTOMY, RANDOMIZED-TRIAL, MERCI TRIAL, PART I, THROMBOLYSIS, INTRAARTERIAL, ULTRASOUND, MANAGEMENT, ALTEPLASE
n4:klicoveSlovo
n5:MECHANICAL%20THROMBECTOMY n5:INTRAARTERIAL n5:THROMBOLYSIS n5:RANDOMIZED-TRIAL n5:TISSUE-PLASMINOGEN-ACTIVATOR n5:PART%20I n5:MANAGEMENT n5:ALTEPLASE n5:ULTRASOUND n5:MERCI%20TRIAL
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[C33342410B2F]
n4:nazevZdroje
CURRENT TREATMENT OPTIONS IN NEUROLOGY
n4:obor
n13:FH
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
2
n4:rokUplatneniVysledku
n8:2010
n4:svazekPeriodika
12
n4:tvurceVysledku
Mikulík, Robert Goldemund, David
s:issn
1092-8480
s:numberOfPages
12