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Statements

Subject Item
n2:RIV%2F00098892%3A_____%2F12%3A%230000647%21RIV14-MZ0-00098892
rdf:type
skos:Concept n7:Vysledek
dcterms:description
Background The current European license for alteplase in acute ischemic stroke excludes from treatment large groups of patients. Nevertheless, in everyday practice, many patients receive off-label thrombolysis at the physician's discretion. Aim Our aim was to evaluate safety and effectiveness of intravenous alteplase in patients not fully adhering to the drug license compared with those treated strictly according to the license in Central and Eastern Europe. Methods We analyzed the data contributed to Safe Implementation of Thrombolysis in Stroke registry from nine countries between February 2003 and February 2010. Statistical analysis included multivariate logistic regression. Background The current European license for alteplase in acute ischemic stroke excludes from treatment large groups of patients. Nevertheless, in everyday practice, many patients receive off-label thrombolysis at the physician's discretion. Aim Our aim was to evaluate safety and effectiveness of intravenous alteplase in patients not fully adhering to the drug license compared with those treated strictly according to the license in Central and Eastern Europe. Methods We analyzed the data contributed to Safe Implementation of Thrombolysis in Stroke registry from nine countries between February 2003 and February 2010. Statistical analysis included multivariate logistic regression.
dcterms:title
Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe
skos:prefLabel
Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe
skos:notation
RIV/00098892:_____/12:#0000647!RIV14-MZ0-00098892
n7:predkladatel
n8:ico%3A00098892
n4:aktivita
n12:R n12:I
n4:aktivity
I, R
n4:cisloPeriodika
8
n4:dodaniDat
n11:2014
n4:domaciTvurceVysledku
n13:3092488
n4:druhVysledku
n5:J
n4:duvernostUdaju
n17:S
n4:entitaPredkladatele
n14:predkladatel
n4:idSjednocenehoVysledku
142766
n4:idVysledku
RIV/00098892:_____/12:#0000647
n4:jazykVysledku
n16:eng
n4:klicovaSlova
ischemic stroke, drug treatment
n4:klicoveSlovo
n9:ischemic%20stroke n9:drug%20treatment
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[1EE21C8FA4CB]
n4:nazevZdroje
International Journal of Stroke
n4:obor
n15:FH
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
6
n4:rokUplatneniVysledku
n11:2012
n4:svazekPeriodika
7
n4:tvurceVysledku
Šaňák, Daniel
s:issn
1747-4930
s:numberOfPages
8