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Statements

Subject Item
n2:RIV%2F00064211%3A_____%2F13%3A%230000225%21RIV14-MZ0-00064211
rdf:type
skos:Concept n15:Vysledek
dcterms:description
The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy. The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy.
dcterms:title
Toxic shock syndrome and persistent immune activation in an HIV-positive patient Toxic shock syndrome and persistent immune activation in an HIV-positive patient
skos:prefLabel
Toxic shock syndrome and persistent immune activation in an HIV-positive patient Toxic shock syndrome and persistent immune activation in an HIV-positive patient
skos:notation
RIV/00064211:_____/13:#0000225!RIV14-MZ0-00064211
n15:predkladatel
n17:ico%3A00064211
n5:aktivita
n11:I n11:S
n5:aktivity
I, S
n5:cisloPeriodika
4
n5:dodaniDat
n6:2014
n5:domaciTvurceVysledku
n12:5649617 n12:3039145 n12:3657507 n12:5207746 n12:5254485 n12:6742483
n5:druhVysledku
n14:J
n5:duvernostUdaju
n10:S
n5:entitaPredkladatele
n7:predkladatel
n5:idSjednocenehoVysledku
111415
n5:idVysledku
RIV/00064211:_____/13:#0000225
n5:jazykVysledku
n16:eng
n5:klicovaSlova
Combined antiretroviral therapy; CD38; HIV infectionHLA-DR, MCP-1, toxic shock syndrome; HLA-DR; toxic shock syndrome
n5:klicoveSlovo
n8:CD38 n8:Combined%20antiretroviral%20therapy n8:toxic%20shock%20syndrome n8:MCP-1 n8:HIV%20infectionHLA-DR n8:HLA-DR
n5:kodStatuVydavatele
AE - Stát Spojené arabské emiráty
n5:kontrolniKodProRIV
[16B500EDAFAB]
n5:nazevZdroje
Current HIV research.
n5:obor
n13:FN
n5:pocetDomacichTvurcuVysledku
6
n5:pocetTvurcuVysledku
6
n5:rokUplatneniVysledku
n6:2013
n5:svazekPeriodika
11
n5:tvurceVysledku
Beran, Ondřej Davidová, Alžběta Arientová, Simona Jilich, David Holub, Michal Rozsypal, Hanuš
n5:wos
000324868700009
s:issn
1570-162X
s:numberOfPages
5