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Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F13%3A10193329%21RIV14-MZ0-00064203
rdf:type
skos:Concept n15:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.5414/CNX77S105
dcterms:description
Objective and design: High- tone external muscle stimulation (HTEMS) ameliorates pain and discomfort of patients with polyneuropathy. Since some patients reported about an urge to urinate during these treatments, the potential effects of HTEMS application on renal function were investigated. For this purpose in healthy subjects, we analyzed in the current study the acute effects of electrotherapy on pa- rameters of renal function. Interventions: 24 healthy volunteers (14 women and 10 men), mean age 26 +- 4 years, were enrolled. The protocol was composed of a run-in period, a pre-treatment period, the active HTEMS treatment period of both lower extremities and the post-treatment period. The duration of each period was 60 min. Urine collection and blood samples were taken at the begin-ning and end of each period. To achieve a sufficient diuresis, the fluid intake was adapted to the amount of diuresis. Param-eters of renal function included diuresis, glomerular filtration rate (endogenous cre- atinine clearance) and absolute and frac-tional sodium excretion. Moreover blood pressure and heart rate were monitored. Results: HTEMS led to a significant in- crease of creatinine clearance and fractional sodium excretion which was limited to the active treatment period. Conclusion: These findings show for the first time that HTEMS can transiently increase glomerular filtra- tion rate associated with a decreased tu- bular sodium reabsorption. The underlying mechanisms are to be elucidated. Objective and design: High- tone external muscle stimulation (HTEMS) ameliorates pain and discomfort of patients with polyneuropathy. Since some patients reported about an urge to urinate during these treatments, the potential effects of HTEMS application on renal function were investigated. For this purpose in healthy subjects, we analyzed in the current study the acute effects of electrotherapy on pa- rameters of renal function. Interventions: 24 healthy volunteers (14 women and 10 men), mean age 26 +- 4 years, were enrolled. The protocol was composed of a run-in period, a pre-treatment period, the active HTEMS treatment period of both lower extremities and the post-treatment period. The duration of each period was 60 min. Urine collection and blood samples were taken at the begin-ning and end of each period. To achieve a sufficient diuresis, the fluid intake was adapted to the amount of diuresis. Param-eters of renal function included diuresis, glomerular filtration rate (endogenous cre- atinine clearance) and absolute and frac-tional sodium excretion. Moreover blood pressure and heart rate were monitored. Results: HTEMS led to a significant in- crease of creatinine clearance and fractional sodium excretion which was limited to the active treatment period. Conclusion: These findings show for the first time that HTEMS can transiently increase glomerular filtra- tion rate associated with a decreased tu- bular sodium reabsorption. The underlying mechanisms are to be elucidated.
dcterms:title
Effects of high-tone external muscle stimulation on renal function in healthy volunteers Effects of high-tone external muscle stimulation on renal function in healthy volunteers
skos:prefLabel
Effects of high-tone external muscle stimulation on renal function in healthy volunteers Effects of high-tone external muscle stimulation on renal function in healthy volunteers
skos:notation
RIV/00064203:_____/13:10193329!RIV14-MZ0-00064203
n15:predkladatel
n16:ico%3A00064203
n3:aktivita
n14:I
n3:aktivity
I
n3:cisloPeriodika
suppl. 13
n3:dodaniDat
n6:2014
n3:domaciTvurceVysledku
n10:7409230 n10:5592542 n10:3610543
n3:druhVysledku
n17:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n5:predkladatel
n3:idSjednocenehoVysledku
71952
n3:idVysledku
RIV/00064203:_____/13:10193329
n3:jazykVysledku
n13:eng
n3:klicovaSlova
Renal sodium transport; Glo-merular filtration rate; Electrotherapy
n3:klicoveSlovo
n4:Renal%20sodium%20transport n4:Electrotherapy n4:Glo-merular%20filtration%20rate
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[ECB41CAA737F]
n3:nazevZdroje
Clinical Nephrology
n3:obor
n12:FE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n6:2013
n3:svazekPeriodika
79
n3:tvurceVysledku
Pecková, Marie Charvát, Jiří Horáčková, Miroslava Havlín, Jan Schück, Otto
s:issn
0301-0430
s:numberOfPages
3
n7:doi
10.5414/CNX77S105