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Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F12%3A8590%21RIV13-MZ0-00064203
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1097/MPG.0b013e318231d984
dcterms:description
Objective: In 2005, the Inflammatory Bowel Disease (IBD) Working Group of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition published consensus guidelines on the diagnostic workup of paediatric IBD, the Porto criteria. According to these guidelines, children suspected of having IBD should undergo an oesophagogastroduodenoscopy (OGD), ileocolonoscopy, and (except in cases of definitive ulcerative colitis) adequate imaging of the small bowel. To audit and evaluate the diagnostic workup of paediatric patients with IBD in Europe, the Working Group created EUROKIDS, a prospective, Web-based registry of newly diagnosed paediatric patients with IBD. Methods: Patients with IBD (ages 0-18 years) were registered in 44 centres in 18 countries. Data on diagnostic workup were analysed according to the year of diagnosis, type of IBD, and centre size. Diagnostic yield of OGD and ileal intubation were evaluated. Results: Between 2004 and 2009, 2087 newly diagnosed patients were correctly registered. Both OGD and ileocolonoscopy had been performed in 64% of all of the patients and increased significantly from year 1 (52 %) to 5 (71%, P<0.001). Small-bowel follow-through use decreased during the years (year 1 n = 213, year 5 n=108; P<0.001), whereas magnetic resonance imaging use increased (year 1 n = 25, year 5 n = 171; P<0.001). Patients diagnosed as having Crohn disease (CD, 59%) and ulcerative colitis (58%) were more likely to have had a complete diagnostic workup than patients diagnosed as having IBD unclassified (45%). In CD, the diagnostic yield of OGD was 7.5% and the yield of ileal intubation was 13%. Conclusions: The quality of diagnostic workup in paediatric patients with IBD increased steadily between 2004 and 2009. Small-bowel imaging by magnetic resonance imaging superseded the use of small-bowel follow-through. OGD and ileal intubation contributed to a definitive diagnosis of CD. Objective: In 2005, the Inflammatory Bowel Disease (IBD) Working Group of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition published consensus guidelines on the diagnostic workup of paediatric IBD, the Porto criteria. According to these guidelines, children suspected of having IBD should undergo an oesophagogastroduodenoscopy (OGD), ileocolonoscopy, and (except in cases of definitive ulcerative colitis) adequate imaging of the small bowel. To audit and evaluate the diagnostic workup of paediatric patients with IBD in Europe, the Working Group created EUROKIDS, a prospective, Web-based registry of newly diagnosed paediatric patients with IBD. Methods: Patients with IBD (ages 0-18 years) were registered in 44 centres in 18 countries. Data on diagnostic workup were analysed according to the year of diagnosis, type of IBD, and centre size. Diagnostic yield of OGD and ileal intubation were evaluated. Results: Between 2004 and 2009, 2087 newly diagnosed patients were correctly registered. Both OGD and ileocolonoscopy had been performed in 64% of all of the patients and increased significantly from year 1 (52 %) to 5 (71%, P<0.001). Small-bowel follow-through use decreased during the years (year 1 n = 213, year 5 n=108; P<0.001), whereas magnetic resonance imaging use increased (year 1 n = 25, year 5 n = 171; P<0.001). Patients diagnosed as having Crohn disease (CD, 59%) and ulcerative colitis (58%) were more likely to have had a complete diagnostic workup than patients diagnosed as having IBD unclassified (45%). In CD, the diagnostic yield of OGD was 7.5% and the yield of ileal intubation was 13%. Conclusions: The quality of diagnostic workup in paediatric patients with IBD increased steadily between 2004 and 2009. Small-bowel imaging by magnetic resonance imaging superseded the use of small-bowel follow-through. OGD and ileal intubation contributed to a definitive diagnosis of CD.
dcterms:title
Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry
skos:prefLabel
Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry
skos:notation
RIV/00064203:_____/12:8590!RIV13-MZ0-00064203
n17:predkladatel
n18:ico%3A00064203
n3:aktivita
n12:I
n3:aktivity
I
n3:cisloPeriodika
3
n3:dodaniDat
n11:2013
n3:domaciTvurceVysledku
n14:2214512 n14:4550315 n14:9714502
n3:druhVysledku
n4:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
130943
n3:idVysledku
RIV/00064203:_____/12:8590
n3:jazykVysledku
n16:eng
n3:klicovaSlova
diagnostic workup; diagnostic yield; inflammatory bowel disease; OGD; paediatrics
n3:klicoveSlovo
n10:diagnostic%20workup n10:diagnostic%20yield n10:OGD n10:inflammatory%20bowel%20disease n10:paediatrics
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[B3F55723A7AF]
n3:nazevZdroje
Journal of Pediatric Gastroenterology and Nutrition
n3:obor
n5:FB
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
45
n3:rokUplatneniVysledku
n11:2012
n3:svazekPeriodika
54
n3:tvurceVysledku
Veereman, G. Buderus, S. Maly, J. Hildebrand, H. Paerregaard, A. Koletzko, S. Finkel, Y. Bie, CI Stordal, K. Murphy, MS Orel, R. Sandhu, BK Sladek, M. Staiano, A. Escher, JC Hugot, J. P. Bronský, Jiří Cucchiara, S. Henker, J. Trindade, E. Dias, J. A. Holmquist, L. Hradský, Ondřej Malmborg, P. Eglite, L. Fell, JM Ridder, L. Socha, P. Bujanover, Y. Ruemmele, F. Roma, E. Veres, G. Lionetti, P. Levine, A. Lazowska, I. Koláček, S. Bochenek, K. Perminow, G. Keller, K. Biervliet, S. Chong, SK Spray, C. Ravelli, A. Nevoral, Jiří Amil, Dias, J
n3:wos
000300760200013
s:issn
0277-2116
s:numberOfPages
7