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Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F12%3A8271%21RIV13-MZ0-00064203
rdf:type
skos:Concept n9:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1016/j.cub.2012.10.039
dcterms:description
The Romani, the largest European minority group with approximately 11 million people [1], constitute a mosaic of languages, religions, and lifestyles while sharing a distinct social heritage. Linguistic [2] and genetic [3-8] studies have located the Romani origins in the Indian subcontinent. However, a genome-wide perspective on Romani origins and population substructure, as well as a detailed reconstruction of their demographic history, has yet to be provided. Our analyses based on genome-wide data from 13 Romani groups collected across Europe suggest that the Romani diaspora constitutes a single initial founder population that originated in north/northwestern India 1.5 thousand years ago (kya). Our results further indicate that after a rapid migration with moderate gene flow from the Near or Middle East, the European spread of the Romani people was via the Balkans starting -0.9 kya. The strong population substructure and high levels of homozygosity we found in the European Romani are in line with genetic isolation as well as differential gene flow in time and space with non-Romani Europeans. Overall, our genome-wide study sheds new light on the origins and demographic history of European Romani. The Romani, the largest European minority group with approximately 11 million people [1], constitute a mosaic of languages, religions, and lifestyles while sharing a distinct social heritage. Linguistic [2] and genetic [3-8] studies have located the Romani origins in the Indian subcontinent. However, a genome-wide perspective on Romani origins and population substructure, as well as a detailed reconstruction of their demographic history, has yet to be provided. Our analyses based on genome-wide data from 13 Romani groups collected across Europe suggest that the Romani diaspora constitutes a single initial founder population that originated in north/northwestern India 1.5 thousand years ago (kya). Our results further indicate that after a rapid migration with moderate gene flow from the Near or Middle East, the European spread of the Romani people was via the Balkans starting -0.9 kya. The strong population substructure and high levels of homozygosity we found in the European Romani are in line with genetic isolation as well as differential gene flow in time and space with non-Romani Europeans. Overall, our genome-wide study sheds new light on the origins and demographic history of European Romani.
dcterms:title
Reconstructing the Population History of European Romani from Genome-wide Data Reconstructing the Population History of European Romani from Genome-wide Data
skos:prefLabel
Reconstructing the Population History of European Romani from Genome-wide Data Reconstructing the Population History of European Romani from Genome-wide Data
skos:notation
RIV/00064203:_____/12:8271!RIV13-MZ0-00064203
n9:predkladatel
n17:ico%3A00064203
n3:aktivita
n18:I
n3:aktivity
I
n3:cisloPeriodika
24
n3:dodaniDat
n5:2013
n3:domaciTvurceVysledku
n7:9104992
n3:druhVysledku
n15:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
164410
n3:idVysledku
RIV/00064203:_____/12:8271
n3:jazykVysledku
n4:eng
n3:klicovaSlova
worldwide human-populations; positive selection; genetic-variation; y-chromosome; patterns; homozygosity; divergence; diversity; lineages; gypsies
n3:klicoveSlovo
n6:diversity n6:homozygosity n6:lineages n6:y-chromosome n6:patterns n6:gypsies n6:divergence n6:positive%20selection n6:genetic-variation n6:worldwide%20human-populations
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[C80CC4FEDAED]
n3:nazevZdroje
Current Biology
n3:obor
n12:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
22
n3:rokUplatneniVysledku
n5:2012
n3:svazekPeriodika
22
n3:tvurceVysledku
Lao, O. Sertic, J. Netea, MG Kayser, M. Metspalu, A. Pamjav, H. Wollstein, A. Marigorta, UM Ioana, M. Radojkovic, D. Ferak, V. Jordanova, A. Kaneva, R. Kucinskas, V. Macek jr., Milan Rolleston, SJH Mendizabal, I. de Pablo, R. Makukh, H. Kouvatsi, A. Comas, D. Gusmao, L.
n3:wos
000312760400025
s:issn
0960-9822
s:numberOfPages
8