This HTML5 document contains 52 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n9http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n14http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
n16http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00064203%3A_____%2F10%3A6259%21RIV11-MZ0-00064203/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n15http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n6http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n13http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F10%3A6259%21RIV11-MZ0-00064203
rdf:type
skos:Concept n14:Vysledek
dcterms:description
This study evaluated quantification of fetal extracellular DNA in maternal plasma for differentiation between cases at risk of onset of placental-insufficiency-related complications and normal pregnancies. Using real-time polymerase chain reaction, fetal (sex-determining region Y [SRY] and hypermethylated RASSF1A sequence) and total (beta-globin [GLO] gene) extracellular DNA was examined in 70 normal pregnancies, 18 at risk of placental-insufficiency-related pregnancy complications, 24 preeclampsia with or without (w or w/o) intrauterine growth retardation (IUGR) (median 34.0 week), and 11 IUGR (median 28.5 week). IUGR was diagnosed when estimated fetal weight was below the 10th percentile for evaluated gestational age. These data indicate that fetal and total extracellular DNA concentrations can be significantly elevated in plasma of patients who later developed placental-insufficiency-related pregnancy complications. This study evaluated quantification of fetal extracellular DNA in maternal plasma for differentiation between cases at risk of onset of placental-insufficiency-related complications and normal pregnancies. Using real-time polymerase chain reaction, fetal (sex-determining region Y [SRY] and hypermethylated RASSF1A sequence) and total (beta-globin [GLO] gene) extracellular DNA was examined in 70 normal pregnancies, 18 at risk of placental-insufficiency-related pregnancy complications, 24 preeclampsia with or without (w or w/o) intrauterine growth retardation (IUGR) (median 34.0 week), and 11 IUGR (median 28.5 week). IUGR was diagnosed when estimated fetal weight was below the 10th percentile for evaluated gestational age. These data indicate that fetal and total extracellular DNA concentrations can be significantly elevated in plasma of patients who later developed placental-insufficiency-related pregnancy complications.
dcterms:title
Quantification of Extracellular DNA Using Hypermethylated RASSF1A, SRY, and GLO Sequences-Evaluation of Diagnostic Possibilities for Predicting Placental Insufficiency Quantification of Extracellular DNA Using Hypermethylated RASSF1A, SRY, and GLO Sequences-Evaluation of Diagnostic Possibilities for Predicting Placental Insufficiency
skos:prefLabel
Quantification of Extracellular DNA Using Hypermethylated RASSF1A, SRY, and GLO Sequences-Evaluation of Diagnostic Possibilities for Predicting Placental Insufficiency Quantification of Extracellular DNA Using Hypermethylated RASSF1A, SRY, and GLO Sequences-Evaluation of Diagnostic Possibilities for Predicting Placental Insufficiency
skos:notation
RIV/00064203:_____/10:6259!RIV11-MZ0-00064203
n4:aktivita
n6:I
n4:aktivity
I
n4:cisloPeriodika
6
n4:dodaniDat
n13:2011
n4:domaciTvurceVysledku
n9:7973179 n9:9930795
n4:druhVysledku
n8:J
n4:duvernostUdaju
n11:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
283612
n4:idVysledku
RIV/00064203:_____/10:6259
n4:jazykVysledku
n15:eng
n4:klicovaSlova
free fetal dna; noninvasive prenatal-diagnosis; quantitative pcr measurement; maternal plasma; growth restriction; pregnant-women; preeclampsia; abnormalities; elevation; marker
n4:klicoveSlovo
n5:abnormalities n5:quantitative%20pcr%20measurement n5:preeclampsia n5:pregnant-women n5:marker n5:noninvasive%20prenatal-diagnosis n5:maternal%20plasma n5:free%20fetal%20dna n5:elevation n5:growth%20restriction
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[9372E985E42E]
n4:nazevZdroje
DNA and Cell Biology
n4:obor
n12:EB
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
9
n4:rokUplatneniVysledku
n13:2010
n4:svazekPeriodika
29
n4:tvurceVysledku
Krofta, L. Vlk, Radovan Hromadníková, I. Jirasek, J. E Jancuskova, T. Kotlabova, K. Zejskova, L. Doucha, Jindřich Dlouha, K.
n4:wos
000278871500004
s:issn
1044-5498
s:numberOfPages
7