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Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F10%3A6213%21RIV11-MZ0-00064203
rdf:type
n16:Vysledek skos:Concept
dcterms:description
An increase in immunoglobulin free light chains (FLC) was recently described in several pathological conditions, including asthma. FLC pathology is classically associated with monoclonal gammopathies. Its association with allergic disorders is surprising and unexplained. We therefore tested a cohort of children with severe atopic dermatitis (SCORAD 50-80) to determine the serum levels of free kappa and lambda chains, and correlated the results with clinical status and relevant laboratory markers. Seventy-three patients with severe forms of AD, all children from 3 months to 3 years of age and ninety healthy age-matched controls were included in the study. An increase in immunoglobulin free light chains (FLC) was recently described in several pathological conditions, including asthma. FLC pathology is classically associated with monoclonal gammopathies. Its association with allergic disorders is surprising and unexplained. We therefore tested a cohort of children with severe atopic dermatitis (SCORAD 50-80) to determine the serum levels of free kappa and lambda chains, and correlated the results with clinical status and relevant laboratory markers. Seventy-three patients with severe forms of AD, all children from 3 months to 3 years of age and ninety healthy age-matched controls were included in the study.
dcterms:title
Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis
skos:prefLabel
Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis Serum Immunoglobulin Free Light Chains in Severe Forms of Atopic Dermatitis
skos:notation
RIV/00064203:_____/10:6213!RIV11-MZ0-00064203
n3:aktivita
n4:Z n4:S n4:I
n3:aktivity
I, S, Z(MSM0021620812), Z(MZ0FNM2005)
n3:cisloPeriodika
4
n3:dodaniDat
n6:2011
n3:domaciTvurceVysledku
n5:6939791 n5:5285593 n5:1287362 n5:6258883 n5:9187502 n5:2682699 n5:4057147
n3:druhVysledku
n15:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
287029
n3:idVysledku
RIV/00064203:_____/10:6213
n3:jazykVysledku
n9:eng
n3:klicovaSlova
inflammatory diseases; ig; immediate; responses; allergy; marker; target; urine; cells
n3:klicoveSlovo
n14:inflammatory%20diseases n14:allergy n14:target n14:immediate n14:ig n14:urine n14:cells n14:marker n14:responses
n3:kodStatuVydavatele
NO - Norské království
n3:kontrolniKodProRIV
[4233E2772B7D]
n3:nazevZdroje
Scandinavian Journal of Immunology
n3:obor
n13:EC
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
8
n3:rokUplatneniVysledku
n6:2010
n3:svazekPeriodika
71
n3:tvurceVysledku
Skalická, Anna Poloučková, Andrea Kayserová, Jana Čapková, Štěpánka Malinova, V. Vernerová, Eva Bartůňková, Jiřina Šedivá, Anna
n3:wos
000275918400012
n3:zamer
n12:MZ0FNM2005 n12:MSM0021620812
s:issn
0300-9475
s:numberOfPages
5