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Statements

Subject Item
n2:RIV%2F00064203%3A_____%2F09%3A5332%21RIV10-MZ0-00064203
rdf:type
n13:Vysledek skos:Concept
dcterms:description
Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinct entities: systemic anaplastic lymphoma kinase (ALK) positive, systemic ALK(-) and cutaneous ALK(-) ALCL (cALCL). Little is known about their pathogenesis and their cellular origin, and morphological and immunophenotypical overlap exists between ALK(-) ALCL and classical Hodgkin lymphoma (cHL). We conducted gene expression profiling of microdissected lymphoma cells of five ALK(+) and four ALK(-) systemic ALCL, seven cALCL and sixteen cHL, and of eight subsets of normal T and NK cells. Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinct entities: systemic anaplastic lymphoma kinase (ALK) positive, systemic ALK(-) and cutaneous ALK(-) ALCL (cALCL). Little is known about their pathogenesis and their cellular origin, and morphological and immunophenotypical overlap exists between ALK(-) ALCL and classical Hodgkin lymphoma (cHL). We conducted gene expression profiling of microdissected lymphoma cells of five ALK(+) and four ALK(-) systemic ALCL, seven cALCL and sixteen cHL, and of eight subsets of normal T and NK cells.
dcterms:title
Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma
skos:prefLabel
Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma
skos:notation
RIV/00064203:_____/09:5332!RIV10-MZ0-00064203
n4:aktivita
n11:V
n4:aktivity
V
n4:cisloPeriodika
11
n4:dodaniDat
n5:2010
n4:domaciTvurceVysledku
n10:3555828
n4:druhVysledku
n16:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
316052
n4:idVysledku
RIV/00064203:_____/09:5332
n4:jazykVysledku
n14:eng
n4:klicovaSlova
anaplastic large cell lymphoma; Hodgkin lymphoma; gene expression profiling; lymphoma pathogenesis; nf-kappa-b; reed-sternberg cells; t-cell; classical hodgkin; molecular-biology; cdna arrays; disease; transcription; promoter; features
n4:klicoveSlovo
n8:promoter n8:classical%20hodgkin n8:molecular-biology n8:transcription n8:anaplastic%20large%20cell%20lymphoma n8:lymphoma%20pathogenesis n8:nf-kappa-b n8:t-cell n8:cdna%20arrays n8:Hodgkin%20lymphoma n8:features n8:gene%20expression%20profiling n8:disease n8:reed-sternberg%20cells
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[6C2136AFCD79]
n4:nazevZdroje
Leukemia
n4:obor
n12:FD
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
16
n4:rokUplatneniVysledku
n5:2009
n4:svazekPeriodika
23
n4:tvurceVysledku
Klapper, W. Bohle, V. Sundstrom, C. Brauninger, A. Kuppers, R. Falini, B. Metzler, D. Willenbrock, K. Doring, C. Hansmann, M. L. Eckerle, S. Paulli, M. Brune, V. Kodet, Roman Chaubert, AB Tiacci, E.
n4:wos
000271666000021
s:issn
0887-6924
s:numberOfPages
10