This HTML5 document contains 47 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n17http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n14http://linked.opendata.cz/resource/domain/vavai/projekt/
n16http://linked.opendata.cz/resource/domain/vavai/subjekt/
n15http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n19http://bibframe.org/vocab/
n12http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00064173%3A_____%2F13%3A%230000339%21RIV14-MZ0-00064173/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n6http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n8http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00064173%3A_____%2F13%3A%230000339%21RIV14-MZ0-00064173
rdf:type
skos:Concept n15:Vysledek
dcterms:description
A release of light neurofilament subunits (NFL) into cerebrospinal fluid (CSF) and serum in multiple sclerosis (MS) may induce an immune response. We examined CSF and serum NFL levels and IgG antibodies against NFL in 19 patients with a clinically isolated syndrome (CIS) early converted into MS, 20 CIS-non-converters, 23 MS patients and 32 controls. CSF NFL levels were significantly higher in all patient groups. The highest CSF or intrathecally (IT) synthesized anti-NFL antibodies and CSF/serum ratios of anti-NFL antibodies were observed in CIS-converters. CSF NFL and CSF or IT anti-NFL antibodies could be surrogate biomarkers of axonal injury in early MS. A release of light neurofilament subunits (NFL) into cerebrospinal fluid (CSF) and serum in multiple sclerosis (MS) may induce an immune response. We examined CSF and serum NFL levels and IgG antibodies against NFL in 19 patients with a clinically isolated syndrome (CIS) early converted into MS, 20 CIS-non-converters, 23 MS patients and 32 controls. CSF NFL levels were significantly higher in all patient groups. The highest CSF or intrathecally (IT) synthesized anti-NFL antibodies and CSF/serum ratios of anti-NFL antibodies were observed in CIS-converters. CSF NFL and CSF or IT anti-NFL antibodies could be surrogate biomarkers of axonal injury in early MS.
dcterms:title
Serum and cerebrospinal fluid light neurofilaments and antibodies against them in clinically isolated syndrome and multiple sclerosis Serum and cerebrospinal fluid light neurofilaments and antibodies against them in clinically isolated syndrome and multiple sclerosis
skos:prefLabel
Serum and cerebrospinal fluid light neurofilaments and antibodies against them in clinically isolated syndrome and multiple sclerosis Serum and cerebrospinal fluid light neurofilaments and antibodies against them in clinically isolated syndrome and multiple sclerosis
skos:notation
RIV/00064173:_____/13:#0000339!RIV14-MZ0-00064173
n15:predkladatel
n16:ico%3A00064173
n3:aktivita
n18:I n18:P
n3:aktivity
I, P(NT13183)
n3:cisloPeriodika
1-2
n3:dodaniDat
n8:2014
n3:domaciTvurceVysledku
n17:1787977 n17:6721427 n17:1402455
n3:druhVysledku
n13:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
104777
n3:idVysledku
RIV/00064173:_____/13:#0000339
n3:jazykVysledku
n11:eng
n3:klicovaSlova
Serum; Multiple sclerosis; Light neurofilament subunit; Clinically isolated syndrome; Cerebrospinal fluid; Antibody
n3:klicoveSlovo
n6:Multiple%20sclerosis n6:Serum n6:Antibody n6:Light%20neurofilament%20subunit n6:Cerebrospinal%20fluid n6:Clinically%20isolated%20syndrome
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[36A058F65300]
n3:nazevZdroje
Journal of Neuroimmunology
n3:obor
n9:FH
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
6
n3:projekt
n14:NT13183
n3:rokUplatneniVysledku
n8:2013
n3:svazekPeriodika
262
n3:tvurceVysledku
Kotoučová, Jolana Bartoš, Aleš Zimová, Denisa
n3:wos
000324970400016
s:issn
0165-5728
s:numberOfPages
8
n19:doi
10.1016/j.jneuroim.2013.06.010