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Statements

Subject Item
n2:RIV%2F00064165%3A_____%2F13%3A10192474%21RIV14-MZ0-00064165
rdf:type
n8:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.3109/09513590.2012.730575
dcterms:description
Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting women of fertile age. It is associated with several risk factors and long-term health consequences. Chronic anovulation combined with relative estrogen excess and consequent prolonged stimulatory effect on the endometrium can lead to the pathogenesis of hormonal dependant carcinoma. PCOS is thus traditionally reported to be associated with increased risk of endometrial, as well as breast and ovarian cancers. This article provides a critical literature review of the relationship between PCOS and the incidence of estrogen-dependant gynecological tumours, and it then discusses whether the commonly cited risk factor association can be substantiated by high quality studies which comply with the requirements of %22evidence-based medicine.%22 Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting women of fertile age. It is associated with several risk factors and long-term health consequences. Chronic anovulation combined with relative estrogen excess and consequent prolonged stimulatory effect on the endometrium can lead to the pathogenesis of hormonal dependant carcinoma. PCOS is thus traditionally reported to be associated with increased risk of endometrial, as well as breast and ovarian cancers. This article provides a critical literature review of the relationship between PCOS and the incidence of estrogen-dependant gynecological tumours, and it then discusses whether the commonly cited risk factor association can be substantiated by high quality studies which comply with the requirements of %22evidence-based medicine.%22
dcterms:title
Is polycystic ovary syndrome, a state of relative estrogen excess, a real risk factor for estrogen-dependant malignancies? Is polycystic ovary syndrome, a state of relative estrogen excess, a real risk factor for estrogen-dependant malignancies?
skos:prefLabel
Is polycystic ovary syndrome, a state of relative estrogen excess, a real risk factor for estrogen-dependant malignancies? Is polycystic ovary syndrome, a state of relative estrogen excess, a real risk factor for estrogen-dependant malignancies?
skos:notation
RIV/00064165:_____/13:10192474!RIV14-MZ0-00064165
n8:predkladatel
n9:ico%3A00064165
n3:aktivita
n18:I
n3:aktivity
I
n3:cisloPeriodika
2
n3:dodaniDat
n10:2014
n3:domaciTvurceVysledku
n14:2443821
n3:druhVysledku
n15:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
81268
n3:idVysledku
RIV/00064165:_____/13:10192474
n3:jazykVysledku
n17:eng
n3:klicovaSlova
polycystic ovary syndrome; estrogen-dependant tumours; estrogens; endometrium; breast; Androgens
n3:klicoveSlovo
n4:endometrium n4:estrogen-dependant%20tumours n4:breast n4:estrogens n4:Androgens n4:polycystic%20ovary%20syndrome
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[601E35B1635E]
n3:nazevZdroje
Gynecological Endocrinology
n3:obor
n19:FK
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
1
n3:rokUplatneniVysledku
n10:2013
n3:svazekPeriodika
29
n3:tvurceVysledku
Fanta, Michael
n3:wos
000313664000015
s:issn
0951-3590
s:numberOfPages
3
n13:doi
10.3109/09513590.2012.730575