This HTML5 document contains 64 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n19http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n16http://linked.opendata.cz/resource/domain/vavai/subjekt/
n15http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
rdfshttp://www.w3.org/2000/01/rdf-schema#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n12http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00064165%3A_____%2F13%3A10192195%21RIV14-MZ0-00064165/
n14http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n5http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00064165%3A_____%2F13%3A10192195%21RIV14-MZ0-00064165
rdf:type
skos:Concept n15:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1212/WNL.0b013e318296e967
dcterms:description
Objective: To compare the frequency of proxy-reported REM sleep behavior disorder (RBD) among relatives of patients with polysomnogram-diagnosed idiopathic RBD (iRBD) in comparison to controls using a large multicenter clinic-based cohort. Methods: A total of 316 patients with polysomnography- confirmed iRBD were recruited from 12 RBD study group centers, along with 316 controls matched on sex and age group. All subjects completed a self-administered questionnaire that collected proxy-reported information on family history of tremor, gait trouble, balance trouble, Parkinson disease, memory loss, and Alzheimer disease. The questionnaire also included a single question that asked about possible symptoms of RBD among first-degree relatives (siblings, parents, and children). Results: A positive family history of dream enactment was reported in 13.8% of iRBD cases compared to 4.8% of controls (odds ratio [OR] = 3.9, 95% confidence interval [CI] 2.0-7.7). ORs were increased for both siblings (OR = 6.1, 95% CI 2.1-18.1) and parents (OR = 3.2, 95% CI 1.4-7.8). We found no significant difference in sex, current age (65.3 +- 10.2 vs 66.9 +- 10.2 years), or age at self-reported RBD onset (55.2 +- 11.7 vs 56.6 +- 15.1 years) in possible familial vs sporadic iRBD. No differences were found in family history of tremor, walking and balance troubles, Parkinson disease, memory loss, or Alzheimer disease. Conclusion: We found increased odds of proxy-reported family history of presumed RBD among individuals with confirmed iRBD. This suggests the possibility of a genetic contribution to RBD Objective: To compare the frequency of proxy-reported REM sleep behavior disorder (RBD) among relatives of patients with polysomnogram-diagnosed idiopathic RBD (iRBD) in comparison to controls using a large multicenter clinic-based cohort. Methods: A total of 316 patients with polysomnography- confirmed iRBD were recruited from 12 RBD study group centers, along with 316 controls matched on sex and age group. All subjects completed a self-administered questionnaire that collected proxy-reported information on family history of tremor, gait trouble, balance trouble, Parkinson disease, memory loss, and Alzheimer disease. The questionnaire also included a single question that asked about possible symptoms of RBD among first-degree relatives (siblings, parents, and children). Results: A positive family history of dream enactment was reported in 13.8% of iRBD cases compared to 4.8% of controls (odds ratio [OR] = 3.9, 95% confidence interval [CI] 2.0-7.7). ORs were increased for both siblings (OR = 6.1, 95% CI 2.1-18.1) and parents (OR = 3.2, 95% CI 1.4-7.8). We found no significant difference in sex, current age (65.3 +- 10.2 vs 66.9 +- 10.2 years), or age at self-reported RBD onset (55.2 +- 11.7 vs 56.6 +- 15.1 years) in possible familial vs sporadic iRBD. No differences were found in family history of tremor, walking and balance troubles, Parkinson disease, memory loss, or Alzheimer disease. Conclusion: We found increased odds of proxy-reported family history of presumed RBD among individuals with confirmed iRBD. This suggests the possibility of a genetic contribution to RBD
dcterms:title
Family history of idiopathic REM behavior disorder a multicenter case-control study Family history of idiopathic REM behavior disorder a multicenter case-control study
skos:prefLabel
Family history of idiopathic REM behavior disorder a multicenter case-control study Family history of idiopathic REM behavior disorder a multicenter case-control study
skos:notation
RIV/00064165:_____/13:10192195!RIV14-MZ0-00064165
n15:predkladatel
n16:ico%3A00064165
n3:aktivita
n13:I
n3:aktivity
I
n3:cisloPeriodika
24
n3:dodaniDat
n5:2014
n3:domaciTvurceVysledku
n19:2043718
n3:druhVysledku
n17:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
74627
n3:idVysledku
RIV/00064165:_____/13:10192195
n3:jazykVysledku
n18:eng
n3:klicovaSlova
polysomnography; Parkinson disease; parent; parasomnia; familial disease; Alzheimer disease; Idiopathic REM sleep behavior disorder
n3:klicoveSlovo
n4:Idiopathic%20REM%20sleep%20behavior%20disorder n4:familial%20disease n4:parent n4:Alzheimer%20disease n4:parasomnia n4:polysomnography n4:Parkinson%20disease
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[68CA22F78D46]
n3:nazevZdroje
Neurology
n3:obor
n8:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
22
n3:rokUplatneniVysledku
n5:2013
n3:svazekPeriodika
80
n3:tvurceVysledku
Postuma, RB Montplaisir, Jacques Jennum, Poul Miyamoto, Tomoyuki Frauscher, Birgit Högl, Birgit Šonka, Karel Wolfson, Christina Desautels, Alex Oertel, Wolfgang Miyamoto, Masayuki Arnulf, Isabelle Fantini, Maria Livia Dauvilliers, Yves Leu-Semenescu, Smeranda Zucconi, Marco Terzaghi, Michele Ferini-Strambi, Luigi Unger, Marcus Puligheddu, Monica Manni, Raffaele Pelletier, Amélie
n3:wos
000330733500014
s:issn
0028-3878
s:numberOfPages
3
n14:doi
10.1212/WNL.0b013e318296e967