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Statements

Subject Item
n2:RIV%2F00064165%3A_____%2F12%3A12877%21RIV13-MZ0-00064165
rdf:type
n12:Vysledek skos:Concept
rdfs:seeAlso
http://www.biomed.cas.cz/physiolres/pdf/61%20Suppl%201/61_S109.pdf
dcterms:description
The article gives an overview of developmental aspects of the ontogeny of pain both in experimental models and in children. The whole article is devoted to the ontogenesis in pain perception and the possible influence on it. The role of endogenous opioids on the development of pain and other important substances such as serotonin, nerve growth factor (NGF) and nicotine are mentioned. There are also important differences of the ontogenesis of thermal and mechanical nociceptive stimulation. The physiological and pathophysiological findings are the backgrounds for principles of treatment, taking into account the special status of analgesics during ontogeny. In particular there are mentioned the special effects of endogenous opioids and especially morphine. It describes the role of vitamin D and erythropoietin during the development of pain perception. This article also mentioned the critical developmental periods in relation to the perception of pain. The attention is paid to stress and immunological changes during the ontogeny of pain. Another important role is played by microglia. The work is concluded by some statements about the use of physiological and pathophysiological findings cluing the treatment of pain in pediatric practice. Codein analgesia is also described because codein starts to be very modern drug with the dependence. The article gives an overview of developmental aspects of the ontogeny of pain both in experimental models and in children. The whole article is devoted to the ontogenesis in pain perception and the possible influence on it. The role of endogenous opioids on the development of pain and other important substances such as serotonin, nerve growth factor (NGF) and nicotine are mentioned. There are also important differences of the ontogenesis of thermal and mechanical nociceptive stimulation. The physiological and pathophysiological findings are the backgrounds for principles of treatment, taking into account the special status of analgesics during ontogeny. In particular there are mentioned the special effects of endogenous opioids and especially morphine. It describes the role of vitamin D and erythropoietin during the development of pain perception. This article also mentioned the critical developmental periods in relation to the perception of pain. The attention is paid to stress and immunological changes during the ontogeny of pain. Another important role is played by microglia. The work is concluded by some statements about the use of physiological and pathophysiological findings cluing the treatment of pain in pediatric practice. Codein analgesia is also described because codein starts to be very modern drug with the dependence.
dcterms:title
Ontogeny of the Pain Ontogeny of the Pain
skos:prefLabel
Ontogeny of the Pain Ontogeny of the Pain
skos:notation
RIV/00064165:_____/12:12877!RIV13-MZ0-00064165
n12:predkladatel
n16:ico%3A00064165
n3:aktivita
n14:I
n3:aktivity
I
n3:cisloPeriodika
1
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n13:5230128
n3:druhVysledku
n15:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
156589
n3:idVysledku
RIV/00064165:_____/12:12877
n3:jazykVysledku
n11:eng
n3:klicovaSlova
Pain; Ontogeny; Pathophysiology; Clinical features; Treatment; electric-stimulation test; neuropathic pain; functional-development; receptive-fields; nervous-system; neonatal-rats; spinal-cord; back-pain; morphine; stress
n3:klicoveSlovo
n4:stress n4:morphine n4:back-pain n4:receptive-fields n4:Pain n4:Treatment n4:Ontogeny n4:spinal-cord n4:functional-development n4:neuropathic%20pain n4:Clinical%20features n4:neonatal-rats n4:nervous-system n4:electric-stimulation%20test n4:Pathophysiology
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[DCA9F1744E6B]
n3:nazevZdroje
Physiological Research
n3:obor
n5:FP
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n7:2012
n3:svazekPeriodika
61
n3:tvurceVysledku
Rokyta, R. Fricová, Jitka
n3:wos
000307133700008
s:issn
0862-8408
s:numberOfPages
14