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Statements

Subject Item
n2:RIV%2F00027162%3A_____%2F10%3A%230000650%21RIV11-GA0-00027162
rdf:type
skos:Concept n17:Vysledek
dcterms:description
The aim of this study was to characterize both cell-mediated and antibody response in rabbits after experimental infection with Encephalitozoon cuniculi using two different infection routes: oral and ocular. SPF rabbits were infected with low and high infection doses. Monitored parameters included clinical signs, detection of spores in urine, antibody response detected with ELISA, and cell-mediated immunity detected by antigen-driven lymphocyte proliferation. At week 13 post infection, half of the rabbits in each group were suppressed by intramuscularly administration of dexamethasone. At week 18 post infection, animals were euthanized. Clinical signs were mild with exacerbation after immunosuppression. Spores in urine and antigen-specific cell-mediated immunity were detected from week 5 and 4 post infection, respectively. Specific IgM were detected one week after infection, and IgG antibodies followed one week later in rabbits infected with the high dose. The aim of this study was to characterize both cell-mediated and antibody response in rabbits after experimental infection with Encephalitozoon cuniculi using two different infection routes: oral and ocular. SPF rabbits were infected with low and high infection doses. Monitored parameters included clinical signs, detection of spores in urine, antibody response detected with ELISA, and cell-mediated immunity detected by antigen-driven lymphocyte proliferation. At week 13 post infection, half of the rabbits in each group were suppressed by intramuscularly administration of dexamethasone. At week 18 post infection, animals were euthanized. Clinical signs were mild with exacerbation after immunosuppression. Spores in urine and antigen-specific cell-mediated immunity were detected from week 5 and 4 post infection, respectively. Specific IgM were detected one week after infection, and IgG antibodies followed one week later in rabbits infected with the high dose.
dcterms:title
Experimental oral and ocular Encephalitozoon cuniculi infection in rabbits Experimental oral and ocular Encephalitozoon cuniculi infection in rabbits
skos:prefLabel
Experimental oral and ocular Encephalitozoon cuniculi infection in rabbits Experimental oral and ocular Encephalitozoon cuniculi infection in rabbits
skos:notation
RIV/00027162:_____/10:#0000650!RIV11-GA0-00027162
n3:aktivita
n7:P n7:V n7:Z
n3:aktivity
P(ED0006/01/01), P(GP524/08/P568), V, Z(MZE0002716202)
n3:cisloPeriodika
12
n3:dodaniDat
n5:2011
n3:domaciTvurceVysledku
n11:1369369 n11:7153643 n11:7362366 n11:6502415 n11:3923673 n11:7988370 n11:5137365
n3:druhVysledku
n8:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
258320
n3:idVysledku
RIV/00027162:_____/10:#0000650
n3:jazykVysledku
n12:eng
n3:klicovaSlova
encephalitozoonosis; ocular infection; antibodies; serology; cell immunity
n3:klicoveSlovo
n9:ocular%20infection n9:encephalitozoonosis n9:serology n9:cell%20immunity n9:antibodies
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[1E12016F7CFE]
n3:nazevZdroje
Parasitology
n3:obor
n18:GJ
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
8
n3:projekt
n16:GP524%2F08%2FP568 n16:ED0006%2F01%2F01
n3:rokUplatneniVysledku
n5:2010
n3:svazekPeriodika
137
n3:tvurceVysledku
Kummer, Vladimír Faldyna, Martin Jeklová, Edita Mašková, Jarmila Kovařčík, Kamil Matiašovic, Ján Škorič, M. Levá, Lenka
n3:wos
000283794600003
n3:zamer
n13:MZE0002716202
s:issn
0031-1820
s:numberOfPages
9