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Statements

Subject Item
n2:RIV%2F00027162%3A_____%2F10%3A%230000642%21RIV11-GA0-00027162
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Using a combination of differential staining and molecular cytogenetic techniques we provide the first description of the four-horned antelope karyotype, draw phylogenetic inferences from the cytogenetic data and discuss possible mechanisms underlying the formation of the tandem fusions in this species. We show (i) pairs 1-6 of Tetracerus correspond to a combination of B. taurus orthologous chromosomes that are tandemly fused head to tail, (ii) the presence of interstitial centromeric satellite DNA at the junctions of orthologous blocks defined by the cross-species painting data and (iii), that in some instances residual telomeric sequences persist at these sites. We conclude that the attendant result of each fusion is an enlarged acrocentric fusion element comprising a single functional centromere and two terminal telomeres that, collectively, led to a reduction of the 2n=58 bovid ancestral acrocentric chromosomal complement to the 2n-38 detected in the four-horned antelope. Using a combination of differential staining and molecular cytogenetic techniques we provide the first description of the four-horned antelope karyotype, draw phylogenetic inferences from the cytogenetic data and discuss possible mechanisms underlying the formation of the tandem fusions in this species. We show (i) pairs 1-6 of Tetracerus correspond to a combination of B. taurus orthologous chromosomes that are tandemly fused head to tail, (ii) the presence of interstitial centromeric satellite DNA at the junctions of orthologous blocks defined by the cross-species painting data and (iii), that in some instances residual telomeric sequences persist at these sites. We conclude that the attendant result of each fusion is an enlarged acrocentric fusion element comprising a single functional centromere and two terminal telomeres that, collectively, led to a reduction of the 2n=58 bovid ancestral acrocentric chromosomal complement to the 2n-38 detected in the four-horned antelope.
dcterms:title
A paradox revealed: karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis) A paradox revealed: karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis)
skos:prefLabel
A paradox revealed: karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis) A paradox revealed: karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis)
skos:notation
RIV/00027162:_____/10:#0000642!RIV11-GA0-00027162
n3:aktivita
n10:Z n10:P
n3:aktivity
P(GAP506/10/0421), Z(MZE0002716202)
n3:cisloPeriodika
2
n3:dodaniDat
n11:2011
n3:domaciTvurceVysledku
n15:8408033 n15:8164703 n15:4379284 n15:4702077
n3:druhVysledku
n17:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
244847
n3:idVysledku
RIV/00027162:_____/10:#0000642
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Chromosome painting; tandem fusion; centromeres; telomeres; repeated sequences
n3:klicoveSlovo
n4:repeated%20sequences n4:centromeres n4:telomeres n4:Chromosome%20painting n4:tandem%20fusion
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[6D142BA81650]
n3:nazevZdroje
Chromosome Research
n3:obor
n18:EB
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
9
n3:projekt
n5:GAP506%2F10%2F0421
n3:rokUplatneniVysledku
n11:2010
n3:svazekPeriodika
18
n3:tvurceVysledku
Pagáčová, Eva Černohorská, Halina Hassanin, A. Ropiquet, A. Gerbault-Seureau, M. Bonillo, C. Robinson, T. J. Kubíčková, Svatava Rubeš, Jiří
n3:wos
000275952900008
n3:zamer
n8:MZE0002716202
s:issn
0967-3849
s:numberOfPages
10