This HTML5 document contains 53 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n12http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00027162%3A_____%2F10%3A%230000628%21RIV11-AV0-00027162/
n17http://linked.opendata.cz/resource/domain/vavai/projekt/
n7http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n18http://linked.opendata.cz/ontology/domain/vavai/
n10http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n11http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n13http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00027162%3A_____%2F10%3A%230000628%21RIV11-AV0-00027162
rdf:type
skos:Concept n18:Vysledek
dcterms:description
The purpose of the present study was to investigate the impact of carcinogenic polycyclic aromatic hydrocarbons and volatile organic compounds on sperm quality in a group of city policemen in Prague. Polymorphisms in metabolic genes folic acid metabolism genes and DNA repair genes were evaluated in these men. The study population was a group of 47 policemen working in the center of the city. No significant differences were found in any of the standard semen parameters between the sampling periods except for vitality of sperms. DNA Fragmentation Index (DFI) were significantly higher in winter than in spring samples for all men and for non-smokers. At the bivariate level, significant associations between hDFI or detDFI and polymorphisms of the repair genes XRCC1, XPD6 and XPD23 were observed. In multivariate models, polymorphisms of the genes XPD6, XPD23 and CYP1A1MspI were associated with high DFI and HDS. Moreover, HDS was significantly associated with polymorphisms in GSTM1 gene. The purpose of the present study was to investigate the impact of carcinogenic polycyclic aromatic hydrocarbons and volatile organic compounds on sperm quality in a group of city policemen in Prague. Polymorphisms in metabolic genes folic acid metabolism genes and DNA repair genes were evaluated in these men. The study population was a group of 47 policemen working in the center of the city. No significant differences were found in any of the standard semen parameters between the sampling periods except for vitality of sperms. DNA Fragmentation Index (DFI) were significantly higher in winter than in spring samples for all men and for non-smokers. At the bivariate level, significant associations between hDFI or detDFI and polymorphisms of the repair genes XRCC1, XPD6 and XPD23 were observed. In multivariate models, polymorphisms of the genes XPD6, XPD23 and CYP1A1MspI were associated with high DFI and HDS. Moreover, HDS was significantly associated with polymorphisms in GSTM1 gene.
dcterms:title
Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution
skos:prefLabel
Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution
skos:notation
RIV/00027162:_____/10:#0000628!RIV11-AV0-00027162
n3:aktivita
n11:P n11:Z
n3:aktivity
P(1QS500390506), Z(AV0Z50390512), Z(AV0Z50390703), Z(MZE0002716202)
n3:cisloPeriodika
1-2
n3:dodaniDat
n13:2011
n3:domaciTvurceVysledku
n7:6821413 n7:8164703 n7:9185682 n7:7029217
n3:druhVysledku
n8:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
260407
n3:idVysledku
RIV/00027162:_____/10:#0000628
n3:jazykVysledku
n9:eng
n3:klicovaSlova
Gene-environment interaction; Sperm DNA damage; Sperm chromatin structure assay; Genetic susceptibility; Carcinogenic polycyclic aromatic hydrocarbons; Volatile organic compounds
n3:klicoveSlovo
n5:Genetic%20susceptibility n5:Carcinogenic%20polycyclic%20aromatic%20hydrocarbons n5:Gene-environment%20interaction n5:Sperm%20DNA%20damage n5:Sperm%20chromatin%20structure%20assay n5:Volatile%20organic%20compounds
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[4057863A8CC5]
n3:nazevZdroje
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
n3:obor
n16:DN
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
7
n3:projekt
n17:1QS500390506
n3:rokUplatneniVysledku
n13:2010
n3:svazekPeriodika
683
n3:tvurceVysledku
Rybář, Roman Chvátalová, I. Rubeš, Jiří Přinosilová, Petra Věžník, Zdeněk Solanský, I. Šrám, R. J.
n3:wos
000273845500002
n3:zamer
n10:MZE0002716202 n10:AV0Z50390703 n10:AV0Z50390512
s:issn
0027-5107
s:numberOfPages
7