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Statements

Subject Item
n2:RIV%2F00027162%3A_____%2F10%3A%230000621%21RIV11-MZE-00027162
rdf:type
n12:Vysledek skos:Concept
dcterms:description
In this study we were interested in the serovars which are frequently isolated from pigs i.e. S. Typhimurium, S. Derby and S. Infantis with porcine pulmonary macrophages. Four hours post addition of bacteria to PAMs, higher numbers of intracellular S. Typhimurium than S. Derby or S. Infantis were observed. However within next 24 hours, counts of S. Typhimurium did not change while S. Derby and S. Infantis increased their counts 10 and 5 times, respectively. The apparent inability of S. Typhimurium to multiply inside PAMs was caused by its higher cytotoxicity. The IL-1beta, IL-8, IL-12p40, IL-23p19 and TNFalpha response to S. Derby and S. Infantis was always higher than to S. Typhimurium. The lower cytokine signaling but higher cytotoxicity of S. Typhimurium for macrophages correlates with the higher virulence for pigs of this serotype when compared with S. Derby or S. Infantis. In this study we were interested in the serovars which are frequently isolated from pigs i.e. S. Typhimurium, S. Derby and S. Infantis with porcine pulmonary macrophages. Four hours post addition of bacteria to PAMs, higher numbers of intracellular S. Typhimurium than S. Derby or S. Infantis were observed. However within next 24 hours, counts of S. Typhimurium did not change while S. Derby and S. Infantis increased their counts 10 and 5 times, respectively. The apparent inability of S. Typhimurium to multiply inside PAMs was caused by its higher cytotoxicity. The IL-1beta, IL-8, IL-12p40, IL-23p19 and TNFalpha response to S. Derby and S. Infantis was always higher than to S. Typhimurium. The lower cytokine signaling but higher cytotoxicity of S. Typhimurium for macrophages correlates with the higher virulence for pigs of this serotype when compared with S. Derby or S. Infantis.
dcterms:title
Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages
skos:prefLabel
Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages
skos:notation
RIV/00027162:_____/10:#0000621!RIV11-MZE-00027162
n3:aktivita
n13:Z n13:P
n3:aktivity
P(ED0006/01/01), P(QH81062), Z(MZE0002716202)
n3:cisloPeriodika
1-2
n3:dodaniDat
n10:2011
n3:domaciTvurceVysledku
n9:9231625 n9:5548721 n9:1703552 n9:9736948 n9:7153643 n9:8456194 n9:7362366
n3:druhVysledku
n16:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
257392
n3:idVysledku
RIV/00027162:_____/10:#0000621
n3:jazykVysledku
n18:eng
n3:klicovaSlova
Derby; Infantis; Typhimurium; pig; macrophage
n3:klicoveSlovo
n8:Typhimurium n8:Infantis n8:macrophage n8:Derby n8:pig
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[754540F029FF]
n3:nazevZdroje
Veterinary Microbiology
n3:obor
n15:GJ
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
7
n3:projekt
n5:QH81062 n5:ED0006%2F01%2F01
n3:rokUplatneniVysledku
n10:2010
n3:svazekPeriodika
140
n3:tvurceVysledku
Rychlík, Ivan Ondráčková, Petra Havlíčková, Hana Faldyna, Martin Volf, Jiří Hradecká, Helena Matiašovic, Ján
n3:wos
000284664800014
n3:zamer
n17:MZE0002716202
s:issn
0378-1135
s:numberOfPages
6