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Statements

Subject Item
n2:RIV%2F00027006%3A_____%2F05%3A2845%21RIV08-MZE-00027006
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Novel acaricidal compounds with inhibitory effects on the digestive enzymes of arthropods are a safe alternative to the traditional neurotoxic pesticides used for control of the stored-product pests. In this work, we explored the properties of acarbose, the low molecular weight inhibitor of -amylases (AI), as a novel acaricide candidate for protection of the stored products from infestation by Acarus siro (Acari: Acaridae). In vitro analysis revealed that AI blocked efficiently the enzymatic activity of digestive amylases of A. siro, and decreased the physiological capacity of mites gut in utilizing a starch component of grain flour. In vivo experiments showed that AI suppressed the population growth of A. siro. The mites were kept for three weeks on experimental diet enriched by AI in concentration range of 0.005 to 0.25%. Population growth of A. siro was negatively correlated with the content of AI in the treated diet with a half-population dose of 0.125%. The suppressive effect of AIs on stored-pr Nízkomolekulární inhbitor akarbóza inhubuje in vitro amylázu skladištního roztoče Acarus siro. Tato inhibice se in vivo projeví blokováním využití škrobu jako potravního zdroje pro tento druh roztoče. Takto ovlivnění roztoči se pomaleji množí, rychlost jejich populačního růstu závisí na koncentraci použitého inhibitoru. Novel acaricidal compounds with inhibitory effects on the digestive enzymes of arthropods are a safe alternative to the traditional neurotoxic pesticides used for control of the stored-product pests. In this work, we explored the properties of acarbose, the low molecular weight inhibitor of -amylases (AI), as a novel acaricide candidate for protection of the stored products from infestation by Acarus siro (Acari: Acaridae). In vitro analysis revealed that AI blocked efficiently the enzymatic activity of digestive amylases of A. siro, and decreased the physiological capacity of mites gut in utilizing a starch component of grain flour. In vivo experiments showed that AI suppressed the population growth of A. siro. The mites were kept for three weeks on experimental diet enriched by AI in concentration range of 0.005 to 0.25%. Population growth of A. siro was negatively correlated with the content of AI in the treated diet with a half-population dose of 0.125%. The suppressive effect of AIs on stored-pr
dcterms:title
In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. In vitro a in vivo inhibice amylázy skladištního roztoče Acarus siro. In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro.
skos:prefLabel
In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. In vitro and in vivo inhibition of -amylases of stored-product mite Acarus siro. In vitro a in vivo inhibice amylázy skladištního roztoče Acarus siro.
skos:notation
RIV/00027006:_____/05:2845!RIV08-MZE-00027006
n3:strany
281;291
n3:aktivita
n4:P n4:Z
n3:aktivity
P(OC 842.20), Z(MZE0002700603)
n3:cisloPeriodika
0
n3:dodaniDat
n11:2008
n3:domaciTvurceVysledku
n6:4892747 n6:7995520 n6:2307596
n3:druhVysledku
n18:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
524472
n3:idVysledku
RIV/00027006:_____/05:2845
n3:jazykVysledku
n15:eng
n3:klicovaSlova
amylase; Acarus siro; Inhibitor; Stored-product mite
n3:klicoveSlovo
n5:amylase n5:Stored-product%20mite n5:Inhibitor n5:Acarus%20siro
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[5DFB4AC68B13]
n3:nazevZdroje
Experimental and Applied Acarology
n3:obor
n14:GF
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
6
n3:projekt
n12:OC%20842.20
n3:rokUplatneniVysledku
n11:2005
n3:svazekPeriodika
35
n3:tvurceVysledku
Křížková Kudlíková, Iva Hubert, Jan Dolečková, L. Stejskal, Václav Mareš, M. Hýblová, J.
n3:zamer
n17:MZE0002700603
s:issn
0168-8162
s:numberOfPages
11