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Statements

Subject Item
n2:RIV%2F00023752%3A_____%2F14%3A43914614%21RIV15-GA0-00023752
rdf:type
n6:Vysledek skos:Concept
rdfs:seeAlso
http://www.ebooks.benthamscience.com/book/9781608058525
dcterms:description
Investigations of alterations in brain asymmetry often focus on the planum temporale of patients with schizophrenia. Data also suggest changes in laterality of demented patients associated with a more marked impairment of the left hemisphere. Our study was performed on autoptic brain tissue of 84 patients, out of which there were 25 nondemented nonpsychotic controls, 50 demented patients (34 Alzheimer disease, 9 multi - infarct dementia and 7 mixed-type dementia patients) and 9 people with schizophrenia. The plana temporalia were evaluated via a new volumetric method using dental resin matter. Areas, cortical thickness and volumes of the right and left planum temporale were evaluated without normalization to brain weight in 60 patients and with normalization in 24 people. In controls, a mild right/left laterality of areas, cortical thickness and volumes was found. Moreover, in control women the areas of the left planum temporale were smaller than those observed in control men. The shifts to left/right laterality of areas and volumes were found in all demented groups. In the more numerous Alzheimer group, the change in laterality of an area was associated with a mild decrease on the right and a mild increase on the left side. In contrast, marked but only bilateral area shrinkage as well as reduced cortical thickness and brain volumes were observed in schizophrenic patients. Investigations of alterations in brain asymmetry often focus on the planum temporale of patients with schizophrenia. Data also suggest changes in laterality of demented patients associated with a more marked impairment of the left hemisphere. Our study was performed on autoptic brain tissue of 84 patients, out of which there were 25 nondemented nonpsychotic controls, 50 demented patients (34 Alzheimer disease, 9 multi - infarct dementia and 7 mixed-type dementia patients) and 9 people with schizophrenia. The plana temporalia were evaluated via a new volumetric method using dental resin matter. Areas, cortical thickness and volumes of the right and left planum temporale were evaluated without normalization to brain weight in 60 patients and with normalization in 24 people. In controls, a mild right/left laterality of areas, cortical thickness and volumes was found. Moreover, in control women the areas of the left planum temporale were smaller than those observed in control men. The shifts to left/right laterality of areas and volumes were found in all demented groups. In the more numerous Alzheimer group, the change in laterality of an area was associated with a mild decrease on the right and a mild increase on the left side. In contrast, marked but only bilateral area shrinkage as well as reduced cortical thickness and brain volumes were observed in schizophrenic patients.
dcterms:title
Planum temporale analysis via a new volumetric method in autoptic brains of demented and psychotic patients Planum temporale analysis via a new volumetric method in autoptic brains of demented and psychotic patients
skos:prefLabel
Planum temporale analysis via a new volumetric method in autoptic brains of demented and psychotic patients Planum temporale analysis via a new volumetric method in autoptic brains of demented and psychotic patients
skos:notation
RIV/00023752:_____/14:43914614!RIV15-GA0-00023752
n3:aktivita
n14:P
n3:aktivity
P(GBP304/12/G069)
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n8:8377146 n8:8482705 n8:5371619 n8:4549600
n3:druhVysledku
n19:C
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
36768
n3:idVysledku
RIV/00023752:_____/14:43914614
n3:jazykVysledku
n18:eng
n3:klicovaSlova
volumetry; schizophrenia; planum temporale; dementia; brain laterality
n3:klicoveSlovo
n17:schizophrenia n17:planum%20temporale n17:brain%20laterality n17:dementia n17:volumetry
n3:kontrolniKodProRIV
[A070A7ED350C]
n3:mistoVydani
Bussum
n3:nazevEdiceCisloSvazku
Advances in Alzheimer`s Research
n3:nazevZdroje
Advances in Alzheimer`s Research
n3:obor
n20:FH
n3:pocetDomacichTvurcuVysledku
4
n3:pocetStranKnihy
447
n3:pocetTvurcuVysledku
9
n3:projekt
n11:GBP304%2F12%2FG069
n3:rokUplatneniVysledku
n7:2014
n3:tvurceVysledku
Mrzílková, Jana Selinger, Pavel Majer, Emerich Řípová, Daniela Krištofiková, Zdena Zach, Petr Kenney, Jana Kutová, Martina Španiel, Filip
s:numberOfPages
19
n16:doi
10.2174/9781608058525114020001
n5:hasPublisher
Bentham Science Publishers Ltd.
n15:isbn
978-1-60805-852-5