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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F12%3A00010462%21RIV13-MZ0-00023736
rdf:type
n15:Vysledek skos:Concept
dcterms:description
CEBPα induces myeloid differentiation via up-regulation of specific genes involved in granulocyte maturation and in inhibition of myeloid cell proliferation. CEBPA is intronless and generates two isoforms as a result of the differential utilization of alternate translation start codon. CEBPα p30 inhibits DNA binding of CEBPα p42 and its transactivation fiction in the expression of key genes in granulocytic differentiation. CEBPA mutation a methylation of its promoter were detected in acute myeloid leukemia and have prognostic significance. CEBPα induces myeloid differentiation via up-regulation of specific genes involved in granulocyte maturation and in inhibition of myeloid cell proliferation. CEBPA is intronless and generates two isoforms as a result of the differential utilization of alternate translation start codon. CEBPα p30 inhibits DNA binding of CEBPα p42 and its transactivation fiction in the expression of key genes in granulocytic differentiation. CEBPA mutation a methylation of its promoter were detected in acute myeloid leukemia and have prognostic significance.
dcterms:title
The essential transcription factor for granulocyte differentiation, CCAAT/enhancer binding protein alpha (CEBPA), and its mutations or inhibition associated with acute myeloid leukemias The essential transcription factor for granulocyte differentiation, CCAAT/enhancer binding protein alpha (CEBPA), and its mutations or inhibition associated with acute myeloid leukemias
skos:prefLabel
The essential transcription factor for granulocyte differentiation, CCAAT/enhancer binding protein alpha (CEBPA), and its mutations or inhibition associated with acute myeloid leukemias The essential transcription factor for granulocyte differentiation, CCAAT/enhancer binding protein alpha (CEBPA), and its mutations or inhibition associated with acute myeloid leukemias
skos:notation
RIV/00023736:_____/12:00010462!RIV13-MZ0-00023736
n15:predkladatel
n17:ico%3A00023736
n3:aktivita
n13:P n13:Z
n3:aktivity
P(LC06044), Z(MZ0UHKT2005)
n3:dodaniDat
n5:2013
n3:domaciTvurceVysledku
n4:7991401
n3:druhVysledku
n8:C
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
134737
n3:idVysledku
RIV/00023736:_____/12:00010462
n3:jazykVysledku
n7:eng
n3:klicovaSlova
granulocytic differentiation; acute myeloid leukemia; CCAAT/enhancer binding protein alpha
n3:klicoveSlovo
n14:acute%20myeloid%20leukemia n14:CCAAT%2Fenhancer%20binding%20protein%20alpha n14:granulocytic%20differentiation
n3:kontrolniKodProRIV
[05F7EC790B47]
n3:mistoVydani
New York
n3:nazevZdroje
Granulocytes: production, types and roles in disease
n3:obor
n19:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetStranKnihy
142
n3:pocetTvurcuVysledku
1
n3:projekt
n10:LC06044
n3:rokUplatneniVysledku
n5:2012
n3:tvurceVysledku
Fuchs, Ota
n3:zamer
n20:MZ0UHKT2005
s:numberOfPages
36
n12:hasPublisher
Nova Science Publishers
n6:isbn
978-1-61942-806-5