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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F10%3A00008339%21RIV11-MZ0-00023736
rdf:type
n13:Vysledek skos:Concept
dcterms:description
Telomere length was evaluated by terminal repeat fragment method in 66 previously untreated patients with B-chronic lymphocytic leukemia (B-CLL) to ascertain whether telomere shortening was associated with genomic aberrations, immunoglobulin variable heavy chain (IgVH) mutational status, CD38 and ZAP-70 expression, and telomerase activity. Telomere length and telomerase activity in combination with other prognostic parameters complete the risk profile of B-CLL patients and might serve for an easy decision on optimal treatment strategy. Telomere length was evaluated by terminal repeat fragment method in 66 previously untreated patients with B-chronic lymphocytic leukemia (B-CLL) to ascertain whether telomere shortening was associated with genomic aberrations, immunoglobulin variable heavy chain (IgVH) mutational status, CD38 and ZAP-70 expression, and telomerase activity. Telomere length and telomerase activity in combination with other prognostic parameters complete the risk profile of B-CLL patients and might serve for an easy decision on optimal treatment strategy.
dcterms:title
Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia
skos:prefLabel
Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia
skos:notation
RIV/00023736:_____/10:00008339!RIV11-MZ0-00023736
n3:aktivita
n12:P n12:Z
n3:aktivity
P(LC535), P(NR9244), Z(MSM0021620808), Z(MZ0VFN2005)
n3:cisloPeriodika
3
n3:dodaniDat
n7:2011
n3:domaciTvurceVysledku
n4:7529805 n4:6881203 n4:8307946 n4:9564918 n4:3340961 n4:8214824 n4:1811541
n3:druhVysledku
n16:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
292164
n3:idVysledku
RIV/00023736:_____/10:00008339
n3:jazykVysledku
n18:eng
n3:klicovaSlova
B-chronic lymphocytic leukemia; telomere length; telomerase activity; chromosomal aberrations; prognosis
n3:klicoveSlovo
n6:prognosis n6:telomerase%20activity n6:telomere%20length n6:chromosomal%20aberrations n6:B-chronic%20lymphocytic%20leukemia
n3:kodStatuVydavatele
SK - Slovenská republika
n3:kontrolniKodProRIV
[C5BAD146ED37]
n3:nazevZdroje
Neoplasma
n3:obor
n15:FD
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
17
n3:projekt
n9:NR9244 n9:LC535
n3:rokUplatneniVysledku
n7:2010
n3:svazekPeriodika
57
n3:tvurceVysledku
Schwarz, Jiří Lizcová, L. Berková, A. Grosová, L. Cmunt, E. Michalová, Kyra Karban, J. Zemanová, M. Malinová, E. Šárová, Iveta Zemanová, Z. Včelíková, Soňa Březinová, Jana Trněný, M. Tajtlová, J. Izáková, Sylvia Čechová, Hana
n3:wos
000277412800004
n3:zamer
n8:MZ0VFN2005 n8:MSM0021620808
s:issn
0028-2685
s:numberOfPages
7