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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F09%3A00008479%21RIV10-MZ0-00023736
rdf:type
n6:Vysledek skos:Concept
dcterms:description
The ecotropic viral integration site 1 (EVI1) gene was identified as a common locus of retroviral integration in myeloid tumors found in mice. The EVI1 gene is highly conserved through evolution and human gene EVI1 on chromosome 3q26 encodes zinc fingers-containing transcription factor. EVI1 was detected in hematopoietic cells in retrovirus-induced myeloid leukemias in mice, and several reports documented EVI1 expression in human myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations. The ecotropic viral integration site 1 (EVI1) gene was identified as a common locus of retroviral integration in myeloid tumors found in mice. The EVI1 gene is highly conserved through evolution and human gene EVI1 on chromosome 3q26 encodes zinc fingers-containing transcription factor. EVI1 was detected in hematopoietic cells in retrovirus-induced myeloid leukemias in mice, and several reports documented EVI1 expression in human myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations.
dcterms:title
Zinc finger protein EVI1 and its role in normal development and in oncogenesis Zinc finger protein EVI1 and its role in normal development and in oncogenesis
skos:prefLabel
Zinc finger protein EVI1 and its role in normal development and in oncogenesis Zinc finger protein EVI1 and its role in normal development and in oncogenesis
skos:notation
RIV/00023736:_____/09:00008479!RIV10-MZ0-00023736
n3:aktivita
n10:Z n10:P
n3:aktivity
P(LC06044), P(NR9045), Z(MZ0UHKT2005)
n3:dodaniDat
n12:2010
n3:domaciTvurceVysledku
n16:7991401
n3:druhVysledku
n19:C
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
353031
n3:idVysledku
RIV/00023736:_____/09:00008479
n3:jazykVysledku
n18:eng
n3:klicovaSlova
EVI1; myeloid leukemia; transforming growth factor-beta (TGF-ß); colon cancer; chromosomal rearrangement
n3:klicoveSlovo
n4:myeloid%20leukemia n4:EVI1 n4:transforming%20growth%20factor-beta%20%28TGF-%C3%9F%29 n4:colon%20cancer n4:chromosomal%20rearrangement
n3:kontrolniKodProRIV
[56DCD8A56B72]
n3:mistoVydani
Trivandrum
n3:nazevZdroje
Focus on Zinc Finger Protein Research
n3:obor
n17:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetStranKnihy
475
n3:pocetTvurcuVysledku
1
n3:projekt
n5:LC06044 n5:NR9045
n3:rokUplatneniVysledku
n12:2009
n3:tvurceVysledku
Fuchs, Ota
n3:zamer
n7:MZ0UHKT2005
s:numberOfPages
17
n20:hasPublisher
Research Signpost
n14:isbn
978-81-308-0320-3