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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F09%3A00008264%21RIV10-MZ0-00023736
rdf:type
skos:Concept n15:Vysledek
dcterms:description
We derived two TRAIL-resistant HL-60 subclones, HL-60/P1 and HL-60/P2, from a TRAIL-sensitive HL-60 acute promyelocytic leukemia cell line and performed expression proteomics analysis. We identified potential molecular targets for selective elimination of resistant cells and proposed and successfuly tested several treatments leading to selective elimination of TRAIL-resistant cells. We derived two TRAIL-resistant HL-60 subclones, HL-60/P1 and HL-60/P2, from a TRAIL-sensitive HL-60 acute promyelocytic leukemia cell line and performed expression proteomics analysis. We identified potential molecular targets for selective elimination of resistant cells and proposed and successfuly tested several treatments leading to selective elimination of TRAIL-resistant cells.
dcterms:title
Identification of molecular targets for selective elimination of TRAIL-resistant leukemia cells : from spots to in vitro assays using TOP15 charts Identification of molecular targets for selective elimination of TRAIL-resistant leukemia cells : from spots to in vitro assays using TOP15 charts
skos:prefLabel
Identification of molecular targets for selective elimination of TRAIL-resistant leukemia cells : from spots to in vitro assays using TOP15 charts Identification of molecular targets for selective elimination of TRAIL-resistant leukemia cells : from spots to in vitro assays using TOP15 charts
skos:notation
RIV/00023736:_____/09:00008264!RIV10-MZ0-00023736
n3:aktivita
n7:P n7:Z
n3:aktivity
P(GA204/07/0830), P(GA305/09/1390), P(LC06044), P(NR8317), P(NR8930), Z(AV0Z50200510), Z(MSM0021620806), Z(MSM0021620808), Z(MZ0UHKT2005)
n3:cisloPeriodika
22
n3:dodaniDat
n16:2010
n3:domaciTvurceVysledku
n8:6965075 n8:3453642 n8:4207556 n8:6416756
n3:druhVysledku
n18:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
318351
n3:idVysledku
RIV/00023736:_____/09:00008264
n3:jazykVysledku
n13:eng
n3:klicovaSlova
biomedicine; Drug resistance; HL-60; leukemia; TOP15; TRAIL
n3:klicoveSlovo
n6:leukemia n6:HL-60 n6:Drug%20resistance n6:TRAIL n6:biomedicine n6:TOP15
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[47860A2ED7D0]
n3:nazevZdroje
Proteomics
n3:obor
n11:FD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
7
n3:projekt
n5:GA204%2F07%2F0830 n5:LC06044 n5:NR8317 n5:GA305%2F09%2F1390 n5:NR8930
n3:rokUplatneniVysledku
n16:2009
n3:svazekPeriodika
9
n3:tvurceVysledku
Petrák, Jiří Toman, Ondřej Živný, J. Šimonová, T. Halada, P. Čmejla, Radek Klener, Pavel
n3:wos
000272391300001
n3:zamer
n4:MSM0021620808 n4:MSM0021620806 n4:MZ0UHKT2005 n4:AV0Z50200510
s:issn
1615-9853
s:numberOfPages
10