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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F07%3A00007131%21RIV08-MZ0-00023736
rdf:type
skos:Concept n17:Vysledek
dcterms:description
The CCAAT/enhancer binding protein alpha (C/EBPalpha) is a member of a family of leucine zipper transcription factors and plays important roles in myeloid differentiation. Learning more about the precise molecular functions of this transcription factor and how these are affected by leukemogenic mutations should lead to an improved understanding of the cellular functions that are disrupted in patients with acute myeloid leukemia (AML) CCAAT/enhancer binding protein alpha (C/EBPalpha) je členem rodiny transkripčních faktorů obsahujících leucinový zip a hraje důležitou úlohy v diferenciaci myeloidních buněk. Detailnější studium tohoto transkripčního faktoru a jak je ovlivněn mutacemi zahrnutými v leukogeneze by měla usnadnit pochopení jak jsou jeho buněčné funkce porušeny u pacientů s akutní myeloidní leukémií (AML) The CCAAT/enhancer binding protein alpha (C/EBPalpha) is a member of a family of leucine zipper transcription factors and plays important roles in myeloid differentiation. Learning more about the precise molecular functions of this transcription factor and how these are affected by leukemogenic mutations should lead to an improved understanding of the cellular functions that are disrupted in patients with acute myeloid leukemia (AML)
dcterms:title
Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Aktivita transkripčního faktoru C/EBPalpha inhibující růst buněk, jeho úloha v hematopoeze a jeho nádor potlačující a naopak onkogenní vlastnosti u leukémií Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias
skos:prefLabel
Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias Aktivita transkripčního faktoru C/EBPalpha inhibující růst buněk, jeho úloha v hematopoeze a jeho nádor potlačující a naopak onkogenní vlastnosti u leukémií
skos:notation
RIV/00023736:_____/07:00007131!RIV08-MZ0-00023736
n4:strany
97;108
n4:aktivita
n14:P
n4:aktivity
P(NR9045)
n4:cisloPeriodika
3
n4:dodaniDat
n5:2008
n4:domaciTvurceVysledku
n10:7991401
n4:druhVysledku
n13:J
n4:duvernostUdaju
n16:S
n4:entitaPredkladatele
n7:predkladatel
n4:idSjednocenehoVysledku
423706
n4:idVysledku
RIV/00023736:_____/07:00007131
n4:jazykVysledku
n12:eng
n4:klicovaSlova
cell cycle; proliferation; differentiation; leukemia; C/EBPalpha; tumor suppressor
n4:klicoveSlovo
n11:C%2FEBPalpha n11:tumor%20suppressor n11:differentiation n11:cell%20cycle n11:proliferation n11:leukemia
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[633E1FCFA931]
n4:nazevZdroje
Folia Biologica
n4:obor
n15:FD
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
1
n4:projekt
n8:NR9045
n4:rokUplatneniVysledku
n5:2007
n4:svazekPeriodika
53
n4:tvurceVysledku
Fuchs, Ota
s:issn
0015-5500
s:numberOfPages
12