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Statements

Subject Item
n2:RIV%2F00023736%3A_____%2F03%3A00000051%21RIV%2F2004%2FGA0%2FL33004%2FN
rdf:type
skos:Concept n14:Vysledek
dcterms:description
Zinc is an essential trace element required by all living organisms. It plays critical roles in a wide variety of biochemical processes including growth, development and reproduction. In biological systems very little amount of zinc is free in solution. Zinc carries out his biological role as divalent cation bound to proteins. Zinc is a cofactor required for function of over 300 mammalian enzymes from all 6 major functional enzyme classes. In addition over thousand of genes in the human genome encode proteins with zinc finger domains. These proteins function as transcriptional regulators in many cellular events and play also role in protein-protein interactions. In humans, the significance of zinc is illustrated by devastating effect of zinc deficiency inducing dermatitis, diminished immune response, decreased healing and neurological changes. Zinc is an essential trace element required by all living organisms. It plays critical roles in a wide variety of biochemical processes including growth, development and reproduction. In biological systems very little amount of zinc is free in solution. Zinc carries out his biological role as divalent cation bound to proteins. Zinc is a cofactor required for function of over 300 mammalian enzymes from all 6 major functional enzyme classes. In addition over thousand of genes in the human genome encode proteins with zinc finger domains. These proteins function as transcriptional regulators in many cellular events and play also role in protein-protein interactions. In humans, the significance of zinc is illustrated by devastating effect of zinc deficiency inducing dermatitis, diminished immune response, decreased healing and neurological changes.
dcterms:title
Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins.
skos:prefLabel
Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins. Role of zinc in eukaryotic cells, zinc transporters and zinc-containing proteins.
skos:notation
RIV/00023736:_____/03:00000051!RIV/2004/GA0/L33004/N
n3:strany
157;170
n3:aktivita
n15:P
n3:aktivity
P(GA204/00/1059), P(NB6574)
n3:cisloPeriodika
2
n3:dodaniDat
n8:2004
n3:domaciTvurceVysledku
n9:4207556 n9:3073572 n9:1918478 n9:7991401
n3:druhVysledku
n16:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
625938
n3:idVysledku
RIV/00023736:_____/03:00000051
n3:jazykVysledku
n17:eng
n3:klicovaSlova
zinc; metallothionein; transport proteins ZIP and ZnT; zinc finger proteins; gene expression
n3:klicoveSlovo
n12:transport%20proteins%20ZIP%20and%20ZnT n12:zinc n12:zinc%20finger%20proteins n12:gene%20expression n12:metallothionein
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[A507362A58BA]
n3:nazevZdroje
Sborník lékařský
n3:obor
n10:FD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n13:GA204%2F00%2F1059 n13:NB6574
n3:rokUplatneniVysledku
n8:2003
n3:svazekPeriodika
Z104
n3:tvurceVysledku
Vyoral, Daniel Babušiak, Marek Fuchs, Ota Petrák, Jiří
s:issn
0036-5327
s:numberOfPages
14