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Statements

Subject Item
n2:RIV%2F00023728%3A_____%2F11%3A%230001045%21RIV12-MZ0-00023728
rdf:type
n16:Vysledek skos:Concept
dcterms:description
These data demonstrate that JunD is overexpressed in SSc and that JunD is a mediator of the profibrotic effects of TGFβ. Considering that inhibitors of AP-1 signalling have recently been developed and are available for clinical trials in SSc, these findings may have translational implications. These data demonstrate that JunD is overexpressed in SSc and that JunD is a mediator of the profibrotic effects of TGFβ. Considering that inhibitors of AP-1 signalling have recently been developed and are available for clinical trials in SSc, these findings may have translational implications.
dcterms:title
The transcription factor JunD mediates transforming growth factor beta-induced fibroblast activation and fibrosis in systemic sclerosis The transcription factor JunD mediates transforming growth factor beta-induced fibroblast activation and fibrosis in systemic sclerosis
skos:prefLabel
The transcription factor JunD mediates transforming growth factor beta-induced fibroblast activation and fibrosis in systemic sclerosis The transcription factor JunD mediates transforming growth factor beta-induced fibroblast activation and fibrosis in systemic sclerosis
skos:notation
RIV/00023728:_____/11:#0001045!RIV12-MZ0-00023728
n16:predkladatel
n17:ico%3A00023728
n4:aktivita
n12:Z n12:S
n4:aktivity
S, Z(MZ00000023728)
n4:cisloPeriodika
7
n4:dodaniDat
n13:2012
n4:domaciTvurceVysledku
n11:1793845
n4:druhVysledku
n15:J
n4:duvernostUdaju
n14:S
n4:entitaPredkladatele
n19:predkladatel
n4:idSjednocenehoVysledku
235761
n4:idVysledku
RIV/00023728:_____/11:#0001045
n4:jazykVysledku
n18:eng
n4:klicovaSlova
EXTRACELLULAR-MATRIX; DERMAL FIBROSIS; STELLATE CELLS; PROTEIN-1; SCLERODERMA; EXPRESSION; MECHANISMS; INHIBITOR; APOPTOSIS; PROTECTS
n4:klicoveSlovo
n10:SCLERODERMA n10:PROTECTS n10:PROTEIN-1 n10:DERMAL%20FIBROSIS n10:EXTRACELLULAR-MATRIX n10:APOPTOSIS n10:MECHANISMS n10:INHIBITOR n10:STELLATE%20CELLS n10:EXPRESSION
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[E4E09FE1D85A]
n4:nazevZdroje
Annals of the Rheumatoid Diseases
n4:obor
n8:FE
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
11
n4:rokUplatneniVysledku
n13:2011
n4:svazekPeriodika
70
n4:tvurceVysledku
Yaniv, M. Palumbo, K. Zerr, P. Avouac J, J. Schett, G. Tomčík, Michal Vollath, S. Akhmetshina, A. Distler, O. Dees, C. Distler, J.H.W.
n4:wos
000291028800025
n4:zamer
n6:MZ00000023728
s:issn
0003-4967
s:numberOfPages
7
n7:doi
10.1136/ard.2010.148296