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Statements

Subject Item
n2:RIV%2F00023001%3A_____%2F11%3A00002488%21RIV12-MZ0-00023001
rdf:type
n15:Vysledek skos:Concept
dcterms:description
Aim. The association between chronic venous disease (CVD) and atherosclerosis has been intensively investigated. Because data regarding cardiovascular disease in women are sparse, we evaluated the potential association between the symptoms of CVD and cardiovascular risk factors including markers of preclinical atherosclerosis in middle-aged women. Methods. A questionnaire for chronic lower limb venous insufficiency was completed by 902 women, aged 45-54 years, from the general population. At the same time, all women were examined for the presence of cardiovascular risk factors, including the ankle/brachial systolic blood pressure index (ABI) and carotid intima media thickness of the common carotid arteries measured by ultrasound. Differences in cardiovascular risk factors and markers of preclinical atherosclerosis between women with and without symptoms of CVD were evaluated. Results. Symptoms (cramps, aching, edema, disturbance of sleep) suggestive of CVD in the lower extremities were reported by 606 (67.2%) women and 114 (12.6%) reported that those symptoms were severe enough to limit their usual daily activities. A higher prevalence of ABI of less than 0.91 was observed in women with any (P=0.005) or severe (P=0.029) CVD symptoms. A significantly higher prevalence of the following were observed in women with any or severe CVD symptoms: coronary artery disease, history of diabetes mellitus, increased body mass index, waist circumference, serum triglycerides, serum C-reactive protein and lower serum HDL cholesterol. Conclusion. CVD symptoms were strongly associated with a higher prevalence of pathological values of ABI and several other manageable cardiovascular risk factors. These findings support the data that chronic venous disease might also indicate increased risk for atherosclerosis. Aim. The association between chronic venous disease (CVD) and atherosclerosis has been intensively investigated. Because data regarding cardiovascular disease in women are sparse, we evaluated the potential association between the symptoms of CVD and cardiovascular risk factors including markers of preclinical atherosclerosis in middle-aged women. Methods. A questionnaire for chronic lower limb venous insufficiency was completed by 902 women, aged 45-54 years, from the general population. At the same time, all women were examined for the presence of cardiovascular risk factors, including the ankle/brachial systolic blood pressure index (ABI) and carotid intima media thickness of the common carotid arteries measured by ultrasound. Differences in cardiovascular risk factors and markers of preclinical atherosclerosis between women with and without symptoms of CVD were evaluated. Results. Symptoms (cramps, aching, edema, disturbance of sleep) suggestive of CVD in the lower extremities were reported by 606 (67.2%) women and 114 (12.6%) reported that those symptoms were severe enough to limit their usual daily activities. A higher prevalence of ABI of less than 0.91 was observed in women with any (P=0.005) or severe (P=0.029) CVD symptoms. A significantly higher prevalence of the following were observed in women with any or severe CVD symptoms: coronary artery disease, history of diabetes mellitus, increased body mass index, waist circumference, serum triglycerides, serum C-reactive protein and lower serum HDL cholesterol. Conclusion. CVD symptoms were strongly associated with a higher prevalence of pathological values of ABI and several other manageable cardiovascular risk factors. These findings support the data that chronic venous disease might also indicate increased risk for atherosclerosis.
dcterms:title
Association between symptoms of chronic venous disease in the lower extremities and cardiovascular risk factors in middle-aged women Association between symptoms of chronic venous disease in the lower extremities and cardiovascular risk factors in middle-aged women
skos:prefLabel
Association between symptoms of chronic venous disease in the lower extremities and cardiovascular risk factors in middle-aged women Association between symptoms of chronic venous disease in the lower extremities and cardiovascular risk factors in middle-aged women
skos:notation
RIV/00023001:_____/11:00002488!RIV12-MZ0-00023001
n15:predkladatel
n18:ico%3A00023001
n3:aktivita
n16:P
n3:aktivity
P(NR9396)
n3:cisloPeriodika
4
n3:dodaniDat
n7:2012
n3:domaciTvurceVysledku
n6:8748918 n6:3212661 n6:6873472 n6:8692548
n3:druhVysledku
n13:J
n3:duvernostUdaju
n10:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
187319
n3:idVysledku
RIV/00023001:_____/11:00002488
n3:jazykVysledku
n17:eng
n3:klicovaSlova
Risk factors; Atherosclerosis; Women; Middle age
n3:klicoveSlovo
n5:Risk%20factors n5:Women n5:Middle%20age n5:Atherosclerosis
n3:kodStatuVydavatele
IT - Italská republika
n3:kontrolniKodProRIV
[6BCCD81CA5C6]
n3:nazevZdroje
International Angiology
n3:obor
n11:FD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:projekt
n8:NR9396
n3:rokUplatneniVysledku
n7:2011
n3:svazekPeriodika
30
n3:tvurceVysledku
Lánská, Věra Roztočil, Karel Piťha, Jan Auzký, Ondřej
n3:wos
000296032500004
s:issn
0392-9590
s:numberOfPages
7