This HTML5 document contains 72 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n16http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00023001%3A_____%2F10%3A00002386%21RIV11-MZ0-00023001/
n7http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n6http://linked.opendata.cz/resource/domain/vavai/projekt/
n15http://linked.opendata.cz/ontology/domain/vavai/
n18http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n17http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n13http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00023001%3A_____%2F10%3A00002386%21RIV11-MZ0-00023001
rdf:type
n15:Vysledek skos:Concept
dcterms:description
Aims: The present study was performed to evaluate the effects of target disruption of the G-protein-coupled receptor Mas for angiotensin 1-7 [Ang(1-7)] in knockout mice on the course of two-kidney, one-clip (2K1C) Goldblatt hypertension. Methods: Knockout and wild-type mice underwent clipping of one renal artery. Blood pressure (BP) was monitored by radiotelemetry. The mice were either untreated or chronically treated with the superoxide (O-2(-)) scavenger tempol (400 mg/l) or the inhibitor of NADPH oxidase apocynin (1 g/l) administered in drinking water. Results: Knockout mice responded to clipping by accelerated increases in BP and the final BP was significantly higher than that in wildtype mice. Chronic treatment with tempol or apocynin elicited similar antihypertensive effects in 2K1C/knockout as in 2K1C/wild-type mice. Acute nitric oxide synthase inhibition caused greater BP increases in 2K1C/wild-type than in 2K1C/knockout mice. Conclusion: Our present findings support the notion that the angiot Aims: The present study was performed to evaluate the effects of target disruption of the G-protein-coupled receptor Mas for angiotensin 1-7 [Ang(1-7)] in knockout mice on the course of two-kidney, one-clip (2K1C) Goldblatt hypertension. Methods: Knockout and wild-type mice underwent clipping of one renal artery. Blood pressure (BP) was monitored by radiotelemetry. The mice were either untreated or chronically treated with the superoxide (O-2(-)) scavenger tempol (400 mg/l) or the inhibitor of NADPH oxidase apocynin (1 g/l) administered in drinking water. Results: Knockout mice responded to clipping by accelerated increases in BP and the final BP was significantly higher than that in wildtype mice. Chronic treatment with tempol or apocynin elicited similar antihypertensive effects in 2K1C/knockout as in 2K1C/wild-type mice. Acute nitric oxide synthase inhibition caused greater BP increases in 2K1C/wild-type than in 2K1C/knockout mice. Conclusion: Our present findings support the notion that the angiot
dcterms:title
Knockout of angiotensin 1-7 receptor mas worsens the course of two-kidney, one-clip Goldblatt hypertension: Roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II Knockout of angiotensin 1-7 receptor mas worsens the course of two-kidney, one-clip Goldblatt hypertension: Roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II
skos:prefLabel
Knockout of angiotensin 1-7 receptor mas worsens the course of two-kidney, one-clip Goldblatt hypertension: Roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II Knockout of angiotensin 1-7 receptor mas worsens the course of two-kidney, one-clip Goldblatt hypertension: Roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II
skos:notation
RIV/00023001:_____/10:00002386!RIV11-MZ0-00023001
n3:aktivita
n10:Z n10:P n10:N
n3:aktivity
N, P(1M0510), P(GA305/07/0167), P(GC305/07/J004), P(GC305/08/J006), P(GP305/08/P053), P(IAA511700701), P(NS10499), P(NS9703), Z(MZ0IKEM2005)
n3:cisloPeriodika
6
n3:dodaniDat
n13:2011
n3:domaciTvurceVysledku
n7:2884941 n7:7308159 n7:3495795 n7:6500048 n7:8260915 n7:5239826 n7:3718867 n7:8551812 n7:6750656 n7:7160879 n7:9474986
n3:druhVysledku
n11:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
266543
n3:idVysledku
RIV/00023001:_____/10:00002386
n3:jazykVysledku
n17:eng
n3:klicovaSlova
two-kidney, one-clip Goldblatt hypertension; mas receptor knockout mice; nitric oxide deficiency
n3:klicoveSlovo
n4:nitric%20oxide%20deficiency n4:one-clip%20Goldblatt%20hypertension n4:mas%20receptor%20knockout%20mice n4:two-kidney
n3:kodStatuVydavatele
CH - Švýcarská konfederace
n3:kontrolniKodProRIV
[E9D789DF84DD]
n3:nazevZdroje
Kidney and Blood Pressure Research
n3:obor
n14:FA
n3:pocetDomacichTvurcuVysledku
11
n3:pocetTvurcuVysledku
15
n3:projekt
n6:IAA511700701 n6:1M0510 n6:GC305%2F07%2FJ004 n6:NS10499 n6:NS9703 n6:GP305%2F08%2FP053 n6:GA305%2F07%2F0167 n6:GC305%2F08%2FJ006
n3:rokUplatneniVysledku
n13:2010
n3:svazekPeriodika
33
n3:tvurceVysledku
Vaňourková, Zdeňka Kramer, H. J. Husková, Zuzana Bader, M. Opočenský, Martin Santos, R. A. Bürgelová, Marcela Škaroupková, Petra Malý, Jan Mrázová, Iveta Rakušan, Dan Vaněčková, Ivana Červenka, Luděk Netuka, Ivan Alenina, N.
n3:wos
000285702300054
n3:zamer
n18:MZ0IKEM2005
s:issn
1420-4096
s:numberOfPages
13