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Statements

Subject Item
n2:RIV%2F00023001%3A_____%2F09%3A00002756%21RIV12-MZ0-00023001
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000210082
dcterms:description
Background: Coronary calcium score (CCS) is established as an index for the risk of coronary heart disease (CHD). The aim of this prospective study was to assess changes in CCS in patients 1 year after kidney transplantation (KTx). Method: A total of 221 consecutive renal transplant recipients were enrolled in our prospective study (140 males/81 females). CCS was analyzed by spiral multidetector CT at baseline and 1 year after KTx. Bone mineral density (BMD) was measured in the lumbar spine (L-BMD) and femur (F-BMD). Results: The mean CCS was 539 +/- 1,033 at baseline. 33% of the patients had a CCS of 0, and 33% of patients had a CCS of >401. A negative correlation was found between F-BMD and CCS, but no correlation was found between L-BMD and CCS. Using CCS, a positive correlation was found between total cholesterol and the age of patients, but no correlation of CCS was found with other biochemical markers of bone and lipid metabolism. One year after transplantation, the mean CCS was 703 +/- 1,253; in 75% of patients the CCS was the same and 25% had a higher CCS. Conclusion: A high risk of CHD was found in 33% of renal graft recipients. No improvement in CCS was found 1 year after KTx. Background: Coronary calcium score (CCS) is established as an index for the risk of coronary heart disease (CHD). The aim of this prospective study was to assess changes in CCS in patients 1 year after kidney transplantation (KTx). Method: A total of 221 consecutive renal transplant recipients were enrolled in our prospective study (140 males/81 females). CCS was analyzed by spiral multidetector CT at baseline and 1 year after KTx. Bone mineral density (BMD) was measured in the lumbar spine (L-BMD) and femur (F-BMD). Results: The mean CCS was 539 +/- 1,033 at baseline. 33% of the patients had a CCS of 0, and 33% of patients had a CCS of >401. A negative correlation was found between F-BMD and CCS, but no correlation was found between L-BMD and CCS. Using CCS, a positive correlation was found between total cholesterol and the age of patients, but no correlation of CCS was found with other biochemical markers of bone and lipid metabolism. One year after transplantation, the mean CCS was 703 +/- 1,253; in 75% of patients the CCS was the same and 25% had a higher CCS. Conclusion: A high risk of CHD was found in 33% of renal graft recipients. No improvement in CCS was found 1 year after KTx.
dcterms:title
Coronary calcium score in renal transplant recipients Coronary calcium score in renal transplant recipients
skos:prefLabel
Coronary calcium score in renal transplant recipients Coronary calcium score in renal transplant recipients
skos:notation
RIV/00023001:_____/09:00002756!RIV12-MZ0-00023001
n3:aktivita
n15:P
n3:aktivity
P(NR8286)
n3:cisloPeriodika
1
n3:dodaniDat
n10:2012
n3:domaciTvurceVysledku
n6:9287086 n6:3536203 n6:6873472 n6:8540446 n6:5202965 n6:2691280
n3:druhVysledku
n13:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
308373
n3:idVysledku
RIV/00023001:_____/09:00002756
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Vascular calcification; Bone disease; Renal transplantation; Metabolic markers, bone; Bone mineral density; Coronary artery disease
n3:klicoveSlovo
n8:Bone%20mineral%20density n8:bone n8:Metabolic%20markers n8:Bone%20disease n8:Coronary%20artery%20disease n8:Vascular%20calcification n8:Renal%20transplantation
n3:kodStatuVydavatele
CH - Švýcarská konfederace
n3:kontrolniKodProRIV
[3B4B3412C280]
n3:nazevZdroje
Nephron clinical practice
n3:obor
n12:FE
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n9:NR8286
n3:rokUplatneniVysledku
n10:2009
n3:svazekPeriodika
112
n3:tvurceVysledku
Sotorník, Ivo Bubeníček, Petr Teplan, Vladimír Adamec, Miloš Lánská, Věra Kautznerová, Dana
n3:wos
000265627400001
s:issn
1660-2110
s:numberOfPages
8
n18:doi
10.1159/000210082