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Namespace Prefixes

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Statements

Subject Item

n2:NK4906

rdf:type

n6:Projekt

rdfs:seeAlso

http://www.isvav.cz/projectDetail.do?rowId=NK4906

dcterms:description

V I.Ŕßsti chceme ový°it vhodnost spektrofotometrickÚho stanovenÝ stabilnÝch metabolit¨ NO v moŔi(U-NO2/NO3) u pacient¨ po transplantaci kad.ledviny p°i normßlnÝm potransplantaŔnÝm vřvoji i p°i komplikacÝch - CyA toxicitý a rejekci. V II.Ŕßsti chceme v experimentu prokßzat p°Ýznivř vliv p.o. podßvanÚho L-argininu u CyA toxicity i u krysÝho modelu ischemizovanÚ ledviny,simulujÝcÝho stav po Tx, a to i p°i zahßjenÝ terapie L-argininem a× s Ŕasovřm odstupem po vzniku CyA toxicity. In part one,we would like to test the suitability of spectrophotometric determination of stable metabolites of NO in urine (U-NO2/NO3) in patients after cadaveric kidney Tx with a normal post-Tx course and with comlications (CyA toxicity and rejection). In part two,we would like to show in experiment,the beneficial effect of oral L-arginine in CyA toxicity also in a rat model of the ischemic kidney simulating the state after Tx. And this even if initiating therapy with L-arginine after an interval following the onset of CyA toxicity.

dcterms:title

Metabolismus NO a L - argininu po transplantaci kad.ledviny NO and L-arginine metabolism after cadaver renal graft transplantation

skos:notation

NK4906

n3:aktivita

n12:NK

n3:celkovaStatniPodpora

n4:celkovaStatniPodpora

n3:celkoveNaklady

n4:celkoveNaklady

n3:duvernostUdaju

n7:S

n3:fazeProjektu

n15:428555

n3:hlavniObor

n17:FE

n3:partnetrHlavni

n16:ico%3A00023001

n3:pocetKoordinujicichPrijemcu

0

n3:pocetPrijemcu

1

n3:pocetSpoluPrijemcu

0

n3:pocetVysledkuRIV

2

n3:pocetZverejnenychVysledkuVRIV

2

n3:sberDatUcastniciPoslednihoRoku

n11:1999

n3:sberDatUdajeProjZameru

n11:1999

n3:statusZobrazovaneFaze

n8:DRRVK

n3:typPojektu

n13:P

n3:zivotniCyklusProjektu

n9:ZK