About: MLL/MLLT3 Fusion Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • MLL/MLLT3 Fusion Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • MLL/MLLT3 Fusion Gene
NCI_META_CUI
  • CL433131
FULL_SYN
  • MLL-AF9 Fusion GeneSYNCI
  • MLL/AF9 Fusion GeneSYNCI
  • MLL-MLLT3 Fusion GeneSYNCI
  • MLL/MLLT3 Fusion GenePTNCI
DEFINITION
  • A fusion gene that results from a chromosomal translocation t(9;11)(p22;q23) which fuses the 5' half of the MLL gene to the 3' end of the MLLT3 gene. This rearrangement is associated with acute lymphocytic leukemia and other leukemia types.NCI
DesignNote
  • The presence of this fusion gene is associated with a better prognosis for primary leukemia as compared to other 11q23 fusions but it indicates a poor prognosis for secondary cases. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
code
  • C99323
is someValuesFrom of
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