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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Monobenzone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Monobenzone
NSC_Code
  • 33918
UMLS_CUI
  • C0050962
CAS_Registry
  • 103-16-2
Accepted_Therapeutic_Use_For
  • Vitiligo
FDA_UNII_Code
  • 9L2KA76MG5
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39494
PDQ_Closed_Trial_Search_ID
  • 39494
Chemical_Formula
  • C13H12O2
Legacy_Concept_Name
  • Monobenzone
CHEBI_ID
  • CHEBI:34380
FULL_SYN
  • MonobenzoneSYDTPNSC0033918
  • monobenzyl ether of hydroquinoneSYNCI
  • MonobenzonePTNCI
  • MBEHABNCI
  • Monobenzyl ether hydroquinoneSYDTPNSC0033918
  • Hydroquinone monobenzyl etherSYDTPNSC0033918
  • BenoquinBRNCI
  • MONOBENZONEPTFDA9L2KA76MG5
DEFINITION
  • A monobenzyl ether of hydroquinone with topical depigmentation activity. Although the exact mechanism of action of depigmentation is unknown, the metabolites of monobenzone appear to have a cytotoxic effect on melanocytes. Furthermore, the depigmentation effect might be mediated through the inhibition of tyrosinase, which is essential in the synthesis of melanin pigments, thereby causing permanent depigmentation of the skin.NCI
code
  • C992
sameAs
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