About: COL1A1/PDGFB Fusion Protein     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • COL1A1/PDGFB Fusion Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • COL1A1/PDGFB Fusion Protein
NCI_META_CUI
  • CL433035
FULL_SYN
  • Collagen Alpha-1(I) Chain/Platelet-Derived Growth Factor Subunit B Fusion ProteinSYNCI
  • COL1A1-PDGFB Fusion ProteinSYNCI
  • COL1A1/PDGFB Fusion ProteinPTNCI
DEFINITION
  • A fusion protein encoded by the COL1A1/PDGFB fusion gene. This protein is comprised of various portions of the collagen alpha-1(I) chain protein fused to all but the first 21 amino acids of the platelet-derived growth factor subunit B protein.NCI
DesignNote
  • Mutagenesis experiments demonstrated that COL1A1/PDGFB fusion gene expressing cells produced COL1A1/PDGFB precursors chains, which formed dimers and were processed to give active 30 kDa PDGFB-like dimers. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
code
  • C99197
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