About: Decitabine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Decitabine
equivalentClass	nodeID://b631911
Has_Target	DNA Modification Methylases DNA
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name	Decitabine
NSC_Code	127716
UMLS_CUI	C0049065
CAS_Registry	2353-33-5
Accepted_Therapeutic_Use_For	Myelodysplastic Syndrome
In_Clinical_Trial_For	Chronic myelogenous leukemia; Myelodysplastic syndrome
FDA_UNII_Code	776B62CQ27
Contributing_Source	FDA
ALT_DEFINITION	A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It is a type of antimetabolite.NCI-GLOSS
PDQ_Open_Trial_Search_ID	39299
PDQ_Closed_Trial_Search_ID	39299
Chemical_Formula	C8H12N4O4
Legacy_Concept_Name	Decitabine
CHEBI_ID	CHEBI:50131
FULL_SYN	5-Aza-2'-deoxycytidineSNNCI 2'-Deoxy-5-azacytidineSNNCI decitabinePTNCI-GLOSSCDR0000045208 DezocitidineSYNCI DecitabinePTDCP00810 Decitabine for InjectionSYNCI 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-oneSNNCI 5-Aza-2'-deoxycytidineSYDTPNSC0127716 DeoxyazacytidineSYNCI DacogenPTNCI-GLOSSCDR0000508667 5-AzadeoxycytidineSNNCI DacogenBRNCI DECITABINEPTFDA776B62CQ27 5-Aza-2'deoxycytidineSNNCI 5-Aza-2-deoxycytidineSNNCI DecitabinePTNCI
DEFINITION	A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. (NCI04)NCI
code	C981
sameAs	DECITABINE DECITABINE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0062824
is someValuesFrom of	nodeID://b645608 nodeID://b651897 nodeID://b659905 nodeID://b662571 nodeID://b666115 nodeID://b666116 nodeID://b666119 nodeID://b666121
is sameAs of	DECITABINE DECITABINE DECITABINE

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