About: Afimoxifene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Afimoxifene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Afimoxifene
UMLS_CUI
  • C0048403
CAS_Registry
  • 68047-06-3
  • 68392-35-8
FDA_UNII_Code
  • 17197F0KYM
Contributing_Source
  • FDA
ALT_DEFINITION
  • A form of the drug tamoxifen that is made by the body after taking tamoxifen. It can also be made in the laboratory, and may help decrease breast density. A topical form of 4-hydroxytamoxifen is being studied in breast cancer screening.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 371709
PDQ_Closed_Trial_Search_ID
  • 371709
Legacy_Concept_Name
  • _4-Hydroxy-Tamoxifen
CHEBI_ID
  • CHEBI:44616
FULL_SYN
  • AfimoxifenePTNCI
  • AFIMOXIFENEPTFDA17197F0KYM
  • 4-hydroxytamoxifenPTNCI-GLOSSCDR0000386195
  • 4-HydroxytamoxifenPTDCP30509
  • 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenolSNNCI
  • 4-OHTABNCI
  • 4-HydroxytamoxifenSYNCI
  • 4-Hydroxy-TamoxifenSYNCI
DEFINITION
  • A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. Afimoxifene has a higher affinity for the estrogen receptor than tamoxifen, and functions as an antagonist in breast cancer cells.NCI
code
  • C975
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