About: Rosiglitazone Cholinate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Rosiglitazone Cholinate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rosiglitazone Cholinate
NCI_META_CUI
  • CL429464
CAS_Registry
  • 920338-48-3
FDA_UNII_Code
  • 386X2T4SQV
Contributing_Source
  • FDA
Chemical_Formula
  • C18H18N3O3S.C5H14NO
FULL_SYN
  • Rosiglitazone CholinatePTNCI
  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, ((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedionate (1:1)SNNCI
  • ROSIGLITAZONE CHOLINATEPTFDA386X2T4SQV
DEFINITION
  • The cholinate salt form of rosiglitazone, an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. In addition to its ability to lower blood glucose levels, rosiglitazone also exerts anti-inflammatory activity through its ability to inhibit nuclear factor-kappaB (NF-KB) activity and increase I-kappaB levels. In addition, rosiglitazone may cause fluid retention and may worsen congestive heart failure. This agent is also associated with an increased risk of heart attacks.NCI
code
  • C96870
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