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AttributesValues
rdf:type
rdfs:label
  • Etarotene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Etarotene
NCI_META_CUI
  • CL429346
CAS_Registry
  • 87719-32-2
FDA_UNII_Code
  • PD3817FE9N
Contributing_Source
  • FDA
Chemical_Formula
  • C25H32O2S
FULL_SYN
  • Arotinoid Ethyl SulfoneSYNCI
  • Ro 15-1570/000CNNCI
  • Arotinoid Ethyl SulphoneSYNCI
  • 6-((E)-p-(Ethylsulfonyl)-alpha-methylstyryl)-1,2,3,4-tetrahydronaphthaleneSNNCI
  • Naphthalene, 6-(2-(4-(ethylsulfonyl)phenyl)-1-methylethenyl)-1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-, (E)-SNNCI
  • ETAROTENEPTFDAPD3817FE9N
  • EtarotenePTNCI
DEFINITION
  • An ethylsulfonyl derivative of arotinoic acid with differentiation inducing and potential antineoplastic activities. Like other retinoic acid agents, etarotene binds to and activates retinoic acid receptors (RARs), thereby inducing changes in the expression of certain genes leading to cell differentiation and decreased cell proliferation in susceptible cells.NCI
code
  • C96705
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