About: Cordycepin Triphosphate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cordycepin Triphosphate
rdfs:subClassOf
Semantic_Type
  • Antibiotic
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Cordycepin Triphosphate
UMLS_CUI
  • C0046803
CAS_Registry
  • 73-04-1
Legacy_Concept_Name
  • Cordycepin_Triphosphate
CHEBI_ID
  • CHEBI:52316
FULL_SYN
  • Cordycepin TriphosphatePTNCI
  • Cordycepin-5'-triphosphateSNNCI
  • 3'-Deoxyadenosine-5'-(tetrahydrogen triphosphate)SNNCI
DEFINITION
  • The triphosphate salt of Cordycepin, a purine nucleoside antimetabolite analogue and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. Cordycepin incorporates into RNA, and, inhibits RNA chain elongation and synthesis due to the absence of a hydroxyl moiety at the 3' position. Because it is converted to an inactive metabolite by adenosine deaminase, this agent must be administered with an adenosine deaminase inhibitor in order to be effective. Cordycepin has displayed cytotoxicity against some leukemic cell lines in vitro. (NCI04)NCI
code
  • C967
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