About: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
NCI_META_CUI
  • CL428164
PDQ_Open_Trial_Search_ID
  • 688830
PDQ_Closed_Trial_Search_ID
  • 688830
FULL_SYN
  • Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8PTNCI
  • 90Y Anti-CD45 MoAb BC8SYNCI
DEFINITION
  • A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb) BC8 labeled with yttrium 90 (Y90), with potential immunotherapeutic activity. Yttrium Y 90 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein-tyrosine phosphatase expressed on the surface of both normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.NCI
code
  • C95698
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